The Chicago Cubs (3-3), with Cade Horton on the mound, visit the Cleveland Guardians (4-3) who will start Joey Cantillo, at 4:10 p.m. ET on Friday in a series opener.
If you’re intending to watch this game, keep reading for streaming and TV options for the Chicago-Cleveland matchup.
When is Cubs vs. Guardians and when does it start?
This matchup between the Cubs and Guardians will take place on Friday, April 3, 2026. You can expect the opening pitch at 4:10 p.m. ET.
Where to watch Cubs vs. Guardians
The Cubs and Guardians will hit the field at Progressive Field for this matchup on April 3, and if you’d like to catch the event live, get your tickets now from Vivid Seats!
What channel is the game on?
You can catch this game live on CleGuardians.TV and MARQ.
Cubs vs. Guardians Game Preview
Cubs Stats, Odds & Insights
The Cubs have been the moneyline favorite six total times this season. They’ve gone 3-3 in those games.
Chicago averages one home run per game to rank 16th in MLB action with six total home runs.
The Cubs rank 21st in MLB, slugging .356.
Chicago has a 3.50 team ERA that ranks ninth across all MLB pitching staffs.
Cubs pitchers combine for the No. 7 WHIP in baseball (1.093).
Guardians Stats, Odds & Insights
The Guardians have entered the game as underdogs seven times this season and won four of those games.
Cleveland has hit six homers this season, which ranks 16th in the majors.
The Guardians rank 26th in the majors with a .322 team slugging percentage.
Cleveland pitchers have a combined ERA of 3.98 ERA this year, which ranks 16th in MLB.
The Guardians rank 11th in MLB with a combined 1.279 WHIP this season.
Cubs Starter Recent Performance: Cade Horton
Opponent Date IP H R ER K BB vs. Nationals March 28 6.1 4 2 2 4 1Guardians Starter Recent Performance: Joey Cantillo
Opponent Date IP H R ER K BB at Mariners March 28 3.2 4 2 2 5 3Cubs Key Players to Watch
Horton (1-0) pitches for the Cubs to make his second start this season.
His last time out came on Saturday against the Washington Nationals, when the righty threw 6 1/3 innings, surrendering two earned runs while allowing four hits.
He has a 2.84 ERA and 5.7 strikeouts per nine innings while opponents are batting .190 against him over his one appearance this season.
Nico Hoerner leads Chicago with a .318 batting average.
Ian Happ leads Chicago in home runs with three and runs batted in with five.
Alex Bregman has five hits this season and a slash line of .208/.321/.458.
Guardians Key Players to Watch
Cantillo will take to the mound for the Guardians, his second start of the season.
The left-hander last pitched on Sunday, when he threw 3 2/3 innings against the Seattle Mariners, giving up two earned runs.
He has pitched to a 4.91 ERA this season with 12.3 strikeouts per nine innings compared to 7.4 walks per nine across one game.
Chase DeLauter paces the Guardians with four home runs and five runs batted in, while accumulating a team-high batting average of .273.
Jose Ramirez’s five runs batted in pace his team.
Steven Kwan is batting .259 with a double and three walks.
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