Scrubs star Eliza Coupe's latest red carpet photos have sparked concern among her fanbase, with one calling her changing appearance in the new snapshots "deeply concerning."
The actress stepped out for a rare photo op in Los Angeles on March 19, 2025, for the official premiere of Netflix & Shondaland's The Residence—in which she appears in one episode, according to IMDb—at The Egyptian Theatre. There, she wore a slinky handkerchief dress in a sparkling silver-gold material. It secured around her shoulders with thick straps and scooped down in the middle of her chest, with the asymmetrical hemline ending in a centered point around her knees.
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A touch of skin peeked out between the higher portion of the hem and her thigh-high black boots, which matched nicely with the black fur coat that draped off her shoulders.
For glam, she paired a dark smokey eye with a pale pink lip and left her shaggy blond hair falling loose in layers around her face, but it was her neck, collarbone and sternal tattoos, as well as a more gaunt appearance, that fans took note of.
Eliza Coupe at Netflix & Shondaland's "The Residence" Los Angeles Premiere at The Egyptian Theatre on March 19, 2025, in Los Angeles, Calif.Michael Buckner/Getty Images
On social media, somebody reposted the photo as a side-by-side comparison to her time on Scrubs.
"Damn. This is just sad. Scrubs star Eliza Coupe, 43, looked unrecognizable in Hollywood..." they wrote in part.
The X user also implied that her changing appearance "looks like more than just normal aging" and expressed "hope she has family and friends who can check in on her because this is deeply concerning."
"So sad. I hope she's ok," one fan replied, while another agreed it was "a dramatic difference."
"Hollywood kills your soul," someone else suggested. "Sad."
Parade has reached out to Coupe's reps for comment.
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