With the help of the Opta supercomputer, we’re revealing win probabilities for each game throughout the 2025 NFL season.
With several big games that have major playoff implications, Week 16 looks to be another pivotal weekend in the 2025 NFL season.
As of Tuesday, the Los Angeles Rams (23.6%), Philadelphia Eagles (17.7%), Green Bay Packers (16.4%), Seattle Seahawks (11.5%) and Chicago Bears (9.0%) are the most likely to win the NFC – according to the Opta supercomputer.
In the AFC, the Denver Broncos (29.8%), Houston Texans (17.7%), Jacksonville Jaguars (13.6%), New England Patriots (11.5%) and Buffalo Bills (9.4%) have the highest probabilities of winning the conference title.
So who will come out on top in these key matchups? We’ve taken plenty of data, pumped it through the supercomputer and received our win probabilities for each game.
Keep in mind these percentages move throughout the week as things happen, particularly after injuries are sorted out (the following win probabilities were as of Tuesday). And there’s always a small chance of a tie (we had the league’s first draw since 2022 earlier this season).
So no matter if it’s a headliner or a game with nothing on the line, the model unsentimentally beeps its way through its NFL picks. You can always find the win percentages – pregame or live – on the schedule page within our NFL hub.
Thursday’s Predictions
Los Angeles Rams (11-3) at Seattle Seahawks (11-3)
Opta Supercomputer’s Win Probability: TBD Playoff Probabilities: Rams Clinched/Seahawks 99.7% (as of Tuesday) All-Time Regular Season Meetings: Seahawks 28-26 Last Meeting: Rams 21, Seahawks 19 (Nov. 16, 2025)Quick Hit: The Rams are looking for their first three-game win streak on the road against the Seahawks. This is just the third time they have won two straight in Seattle (also 1979-85 and 2017-18). Sean McVay’s six career wins in Seattle (including the postseason) are the most by any coach at the current stadium.
Saturday’s Predictions
Philadelphia Eagles (9-5) at Washington Commanders (4-10)
Opta Supercomputer’s Win Probability: TBD Playoff Probabilities: Eagles 99.1%/Commanders Out All-Time Regular Season Meetings: Commanders 89-85-5 Last Meeting: Eagles 55, Commanders 23 (NFC Champ./Jan. 26, 2025)Green Bay Packers (9-4-1) at Chicago Bears (10-4)
Opta Supercomputer’s Win Probability: TBD Playoff Probabilities: Packers 91.6%/Bears 80.2% All-Time Regular Season Meetings: Packers 108-95-6 Last Meeting: Packers 28, Bears 21 (Dec. 7, 2025)Sunday’s Predictions
Tampa Bay Buccaneers (7-7) at Carolina Panthers (7-7)
Opta Supercomputer’s Win Probability: TBD Playoff Probabilities: Buccaneers 60.6%/Panthers 39.4% All-Time Regular Season Meetings: Panthers 25-24 Last Meeting: Buccaneers 48, Panthers 14 (Dec. 29, 2024)Buffalo Bills (10-4) at Cleveland Browns (3-11)
Opta Supercomputer’s Win Probability: TBD Playoff Probabilities: BillsHence then, the article about nfl predictions picks probabilities and insights for every game in week 16 was published today ( ) and is available on The Analyst ( Middle East ) The editorial team at PressBee has edited and verified it, and it may have been modified, fully republished, or quoted. You can read and follow the updates of this news or article from its original source.
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