The Washington Nationals (65-95) square off against the Chicago White Sox (59-101) on Saturday at Nationals Park at 4:05 p.m. ET.
The Nationals will give the nod to Jake Irvin (9-13, 5.69 ERA), who is eyeing win No. 10 on the season, and the White Sox will turn to Sean Burke (4-11, 4.29 ERA).
Nationals vs. White Sox Pitcher Matchup and Game Info
When: Saturday, September 27, 2025 at 4:05 p.m. ET Where: Nationals Park in Washington D.C. How to watch on TV: MASN2 and CHSN Probable Pitchers: Jake Irvin (Nationals) – 9-13, 5.69 ERA vs Sean Burke (White Sox) – 4-11, 4.29 ERANationals vs. White Sox Odds
Nationals to win: -120 Total: 8.5 runsNationals vs. White Sox Pitcher Performance
Irvin Burke 32 GS 22 9-13 W-L 4-11 5.69 ERA 4.29 174 IP 130 61 BB 62 118 SO 123Nationals Probable Starting Pitcher: Jake Irvin
The Nationals will send Irvin (9-13) out to make his 33rd start of the season as he aims for his 10th win. He is 9-13 with a 5.69 ERA and 118 strikeouts in 174 2/3 innings pitched. The right-hander last pitched on Sunday against the New York Mets, when he tossed 5 1/3 innings, allowing two earned runs while giving up six hits. The 28-year-old has an ERA of 5.69, with 6.1 strikeouts per nine innings, in 32 games this season. Opponents are hitting .272 against him. Irvin has nine quality starts under his belt this year. Irvin is seeking his fourth straight appearance lasting five or more innings. He averages 5.4 innings per appearance on the mound. In three of his appearances this season he did not surrender an earned run.Nationals vs. White Sox Promo Codes
White Sox Probable Starting Pitcher: Sean Burke
The White Sox will send Burke (4-11) to the mound for his 23rd start this season. The right-hander’s last start was on Sunday, when he tossed four innings while giving up two earned runs on six hits in a matchup with the San Diego Padres. The 25-year-old has pitched in 27 games this season with an ERA of 4.29 and 8.5 strikeouts per nine innings, with an opponent batting average of .255. In 22 starts this season, he’s earned a quality start in five of them. In 22 starts, Burke has pitched through or past the fifth inning 14 times. He has a season average of 4.8 frames per outing. He has finished four appearances without allowing an earned run in 27 chances this season.How to Bet on Nationals vs. White Sox
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