The Milwaukee Brewers (95-62) are the underdogs on the moneyline (-104) in Tuesday’s contest with the San Diego Padres (86-71). Game time is set for 9:40 p.m. ET on SDPA and FDSWI. The Brewers are favored against the spread in this one (1.5) with +155 odds.
San Diego is projected to give the ball to Randy Vasquez, while Milwaukee has yet to name a starting pitcher.
Padres vs. Brewers Odds
Padres odds to win: -112 Brewers odds to win: -104 Spread: Brewers -1.5 Total: 8.5 runsPadres vs. Brewers Promo Codes
Game Time and Information
Date: Tuesday, September 23, 2025 Time: 9:40 p.m. ET TV: SDPA and FDSWIWho Will Win Padres vs. Brewers?
Padres and Brewers Betting Trends
The Padres have won 59.1% of the games this season when they were favored on the moneyline (52-36).
In games it has played as moneyline favorites with odds of -112 or shorter, San Diego has a 52-36 record (winning 59.1% of its games).
This season, the Brewers have been the underdog 63 times and won 35, or 55.6%, of those games.
Milwaukee is 30-26 this season when entering a game as the underdog by -104 or more on the moneyline.
In the 157 games in which oddsmakers have set an over/under for the Padres, they have combined with opponents to go over the total 67 times (67-84-6).
Games involving the Brewers have gone over the total set by sportsbooks in 76 of 157 chances this season.
Padres Stats & Insights
The Padres have the No. 19 offense in MLB action scoring 4.3 runs per game (670 total runs).
San Diego is second-worst in MLB action with 143 home runs.
The Padres are seventh in MLB with a .252 batting average.
San Diego’s batters strike out 7.2 times per game, the third-lowest average in the majors.
The pitching staff for the Padres has a collective 8.9 K/9, the fifth-best in the majors.
San Diego’s 3.67 team ERA ranks third among all MLB pitching staffs.
Brewers Stats & Insights
The Brewers have scored 794 runs this season, which ranks second in MLB.
Milwaukee has hit 163 homers this season, which ranks 20th in the majors.
The Brewers rank second in MLB with a .260 team batting average.
Milwaukee ranks sixth in MLB in strikeouts per game with an average of 7.8 Ks per contest.
The Brewers have an 8.9 K/9 this season as a pitching staff, fifth-best in baseball.
Milwaukee pitchers have a combined ERA of 3.62 ERA this year, second-best in baseball.
Padres Key Players to Watch
Vasquez (5-7 with a 3.94 ERA and 74 strikeouts in 125 2/3 innings pitched) gets the start for the Padres, his 26th of the season.
Fernando Tatis Jr. has been key for San Diego with 156 hits, an OBP of .367 plus a slugging percentage of .438.
Manny Machado leads San Diego in home runs with 26 and runs batted in with 93.
Luis Arraez’s batting average of .286 leads all San Diego hitters this season.
Ramon Laureano has collected 123 hits this season and has an OBP of .344. He’s slugging .516 on the year.
Brewers Key Players to Watch
William Contreras is hitting .263 with 28 doubles, 17 home runs and 84 walks.
Christian Yelich’s 29 home runs and 102 runs batted in are both team-highs.
Brice Turang has 26 doubles, two triples, 18 home runs and 62 walks while hitting .286.
Sal Frelick’s .292 batting average is a team-high mark.
Padres and Brewers Injuries
Padres: Xander Bogaerts: 10 Day IL (Foot), Nestor Cortes: 15 Day IL (Elbow), David Morgan: 15 Day IL (Shoulder), Jason Adam: 15 Day IL (Quadricep), Jhony Brito: 60 Day IL (Forearm), Joe Musgrove: 60 Day IL (Elbow)
Brewers: Brandon Woodruff: 15 Day IL (Lat), Trevor Megill: 15 Day IL (Flexor strain), José Quintana: 15 Day IL (Calf), D.L. Hall: 15 Day IL (Oblique), Garrett Mitchell: 60 Day IL (Oblique), Logan Henderson: 60 Day IL (Elbow), Shelby Miller: 60 Day IL (Elbow), Connor Thomas: 60 Day IL (Elbow), Jordan Montgomery: 60 Day IL (Elbow), William Contreras: day-to-day (Hand)
Padres vs. Brewers Prediction
Score Prediction: Brewers 5, Padres 4 Total Prediction: Under 8.5 runsHow to Bet on Padres vs. Brewers
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