The resident who died had neuroinvasive West Nile virus, the most severe form of the disease, a spokesperson for Yolo County Public Health announced on Tuesday.
It was not clear where in the county the person lived or may have been exposed.
Symptoms may include fever, headache, body aches, nausea or vomiting, according to public health officials. Rarer symptoms may include severe neurological illness, which officials said can require hospitalization and can be fatal.
Officials are urging residents to take steps to reduce their risk, including eliminating standing water around their homes and using insect repellent when outdoors.
The county and mosquito district recommend limiting outdoor activity around dawn and dusk, when mosquitoes are most active, and ensuring doors and window screens are in good condition to keep mosquitoes outside.
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