Falling into that camp is Richard Carmody, who arrived in season 4 as an undergraduate vet student and departed towards the end of season 5, after securing a spot on a prestigious research programme in London.
Having spent much of his youth at boarding school, he was somewhat estranged from his biological family. So when arrived in Darrowby on his placement, he found the clan he'd never really had.
"I wish I could take you all with me," he said after delivering the bittersweet news, to which his surrogate family reminded him he would "always have a place" at Skeldale.
With that, he took his leave – and, as we found out in the season 7 premiere, continues to reside in London, where he remains committed to his veterinary studies.
Like Carmody, her younger sister lives in London, where she's studying to become a nurse – hence the need for a long-overdue catch-up while James was busy educating the next generation.
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"It's an incredible honour and shows just how far he has come in ten years, from that wee boy in Glasgow to the experienced vet we see now," said actor Nicholas Ralph, reflecting on his character's journey so far.
"With James, every year is a bit of a roller coaster. It’s rare to stay with a character for such a long time, and it really is a privilege."
View Green Video on the source website"Please tell Mr Carmody I hope he's better soon, sorry I missed him," he replied.
All Creatures Great and Small season 7 will premiere on Thursday 17 September at 9pm on 5. All Creatures Great and Small: Behind the Magic will air at 9pm on Friday 18 September.
Check out more of our Drama coverage or visit our TV Guide and Streaming Guide to find out what's on. For more TV recommendations and reviews listen to The Radio Times Podcast.
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