Tight end George Kittle and defensive end Nick Bosa remain on track to play in the Niners' opener in Australia, but Shanahan isn't sure exactly how much each veteran star will see the field.
"That was a big loss," said Shanahan, whose team also lost defensive end Sam Okuayinonu to a right foot injury. "We've lost two D-linemen pretty much for the year after (final roster) cuts, before the first game, which is going to be a huge challenge. I'm hurting for Alfred. It's real unfortunate for him."
San Francisco 49ers' defensive tackle #95 Alfred Collins attends a training session at AAMI Park in Melbourne on September 7, 2026. Martin Keep / AFP via Getty ImagesCollins was likely to play extensively as the 49ers' probable starting nose tackle this season. and his absence will test the depth on an already thin unit.
"Any D-lineman is a possibility, unless you guys can name some guys we can fly here real quick," Shanahan said.
"He just has to know that there's a light at the end of the tunnel," Bosa said. "I told him I've been through it a few times, so he just needs to take it one day at a time."
"We've got to be smart with that," Shanahan said. "Bosa not practicing as much, Kittle — he's had this whole week — but they both look great. But we definitely have got to be smart with that."
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