Ryan Mountcastle will look to extend his 10-game hitting streak when the Baltimore Orioles (60-70) take on the Boston Red Sox (71-60). The Red Sox are listed as -118 favorites on the moneyline for the contest, which starts at 6:35 p.m. ET Monday, live on MASN and NESN from Oriole Park at Camden Yards.
Baltimore is expected to give the ball to Tomoyuki Sugano, while Boston has yet to name a starting pitcher.
Red Sox vs. Orioles Odds
Red Sox odds to win: -118 Orioles odds to win: +100 Spread: Red Sox -1.5 Total: 9.5 runsRed Sox vs. Orioles Promo Codes
Game Time and Information
Date: Monday, August 25, 2025 Time: 6:35 p.m. ET TV: MASN and NESNWho Will Win Red Sox vs. Orioles?
Red Sox and Orioles Betting Trends
The Red Sox have been favored on the moneyline 77 total times this season. They’ve gone 45-32 in those games.
Boston has gone 40-25 (winning 61.5% of its games) when playing as moneyline favorites of -118 or shorter.
This season, the Orioles have won 32 out of the 68 games, or 47.1%, in which they’ve been the underdog.
Baltimore is 27-30 this season when entering a game as the underdog by +100 or more on the moneyline.
In the 130 games in which oddsmakers have set an over/under for the Red Sox, they have combined with opponents to go over the total 65 times (65-61-4).
The Orioles and their opponents have hit the over in 56 of their 130 games with a total this season.
Red Sox Stats & Insights
The Red Sox have the No. 4 offense in MLB action scoring five runs per game (653 total runs).
Boston averages 1.2 home runs per game to rank 12th in MLB action with 155 total home runs.
The Red Sox’s .253 batting average is fourth-best in MLB.
Boston’s 8.8 strikeouts per game are the fifth-most in the majors.
The Red Sox pitching staff ranks 19th in the majors with a collective 8.3 strikeouts per nine innings.
Boston has the fifth-ranked team ERA among all MLB pitching staffs (3.73).
Orioles Stats & Insights
The Orioles rank 17th in the majors with 567 total runs scored this season.
Baltimore has hit 158 homers this season, which ranks 11th in the majors.
The Orioles’ .241 batting average ranks 21st in the league this season.
Baltimore ranks 21st in MLB in strikeouts per game with an average of 8.6 Ks per contest.
The Orioles have an 8.4 K/9 this season as a pitching staff, which ranks 17th in the big leagues.
Baltimore has pitched to a 4.70 ERA this season, which ranks 26th in baseball.
Red Sox Key Players to Watch
Jarren Duran is batting .257 with 12 home runs and 70 RBI for Boston this season.
Trevor Story is a key run producer for Boston with a .260 average, 20 homers and 82 RBI.
Ceddanne Rafaela has 109 hits this season and a slash line of .249/.293/.421.
Alex Bregman has 97 hits and an OBP of .391 to go with a slugging percentage of .531 this season.
Orioles Key Players to Watch
The Orioles’ Sugano (10-5) will make his 25th start of the season.
Gunnar Henderson leads the Orioles in home runs (16), runs batted in (59) and has accumulated a team-high batting average of .283.
Jackson Holliday is batting .246 with 17 doubles, two triples, 15 home runs and 37 walks.
Colton Cowser is batting .216 with 11 doubles, 11 home runs and 16 walks.
Mountcastle has 14 doubles, four home runs and 11 walks while batting .259.
Red Sox and Orioles Injuries
Red Sox: Rob Refsnyder: 10 Day IL (Oblique), Marcelo Mayer: 10 Day IL (Wrist), Wilyer Abreu: 10 Day IL (Calf), Triston Casas: 60 Day IL (Knee), Justin Slaten: 60 Day IL (Shoulder), Josh Winckowski: 60 Day IL (Elbow), Luis Guerrero: 60 Day IL (Elbow), Kutter Crawford: 60 Day IL (Knee), Patrick Sandoval: 60 Day IL (Elbow), Liam Hendriks: 60 Day IL (Hip), Tanner Houck: 60 Day IL (Flexor), Hunter Dobbins: 60 Day IL (Acl)
Orioles: Jordan Westburg: 10 Day IL (Ankle), Tyler O’Neill: 10 Day IL (Wrist), Adley Rutschman: 10 Day IL (Oblique), Scott Blewett: 15 Day IL (Elbow), Colin Selby: 15 Day IL (Hamstring), Brandon Young: 15 Day IL (Hamstring), Felix Bautista: 60 Day IL (Shoulder), Jorge Mateo: 60 Day IL (Elbow), Albert Suarez: 60 Day IL (Shoulder), Kyle Bradish: 60 Day IL (Elbow), Zach Eflin: 60 Day IL (Back), Cody Poteet: 60 Day IL (Shoulder), Grayson Rodriguez: 60 Day IL (Elbow), Tyler Wells: 60 Day IL (Elbow), Gary Sánchez: 60 Day IL (Knee)
Red Sox vs. Orioles Prediction
Score Prediction: Red Sox 5, Orioles 4 Total Prediction: Under 9.5 runsHow to Bet on Red Sox vs. Orioles
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