Cubs vs. Pirates Prediction: Expert Picks, Odds, Stats & Best Bets – Saturday, August 16, 2025 ...Middle East

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The Pittsburgh Pirates (51-71) and Bryan Reynolds (2 HR in his last game) are underdogs (+168) on the moneyline for their matchup with the Chicago Cubs (68-52) on Saturday at 2:20 p.m. ET on Fox Sports 1, MARQ, and SportsNet PT.

Shota Imanaga will get the ball for Chicago while Pittsburgh will counter with Mike Burrows.

Cubs vs. Pirates Odds

Cubs odds to win: -200 Pirates odds to win: +168 Spread: Cubs -1.5 Total: 9.5 runs

Cubs vs. Pirates Promo Codes

Game Time and Information

Date: Saturday, August 16, 2025 Time: 2:20 p.m. ET TV: Fox Sports 1, MARQ, and SportsNet PT

Who Will Win Cubs vs. Pirates?

Cubs and Pirates Betting Trends

The Cubs have been the moneyline favorite 84 total times this season. They’ve finished 54-30 in those games.

Chicago has gone 13-2 when playing as moneyline favorites with odds of -200 or shorter (86.7% winning percentage).

The Pirates have entered the game as underdogs 84 times this season and won 34, or 40.5%, of those games.

Pittsburgh has entered 17 games this season as the underdog by +168 or more and is 6-11 in those contests.

The Cubs have played in 120 games with a set over/under, and have combined with their opponents to go over the total 58 times (58-57-5).

The Pirates and their opponents have hit the over in 52 of their 121 games with a total this season.

Cubs Stats & Insights

The Cubs have the No. 5 offense in baseball scoring five runs per game (605 total runs).

Chicago averages 1.4 home runs per game to rank sixth in MLB action with 170 total home runs.

The Cubs’ .252 batting average is seventh-best in the majors.

Chicago strikes out 7.8 times per game, the fourth-fewest average in MLB.

The 7.7 strikeouts per nine innings put together by the Cubs pitching staff ranks 28th in the majors.

Chicago has the 13th-ranked team ERA among all MLB pitching staffs (3.86).

Pirates Stats & Insights

The Pirates are among the lowest scoring teams in the league, ranking last with just 432 total runs (3.5 per game) this season.

Pittsburgh has hit just 86 homers this season, which ranks last in the majors.

The Pirates have a team batting average of just .232 this season, which ranks 26th among MLB teams.

Pittsburgh ranks 25th with an average of 8.6 strikeouts per game.

The Pirates have a 7.9 K/9 this season as a pitching staff, which ranks 25th in the majors.

Pittsburgh has the 17th-ranked ERA (4.07) in the majors this season.

Cubs Key Players to Watch

The Cubs will send Imanaga (8-5) out for his 18th start of the season. He is 8-5 with a 3.19 ERA and 79 strikeouts through 96 2/3 innings pitched.

Kyle Tucker has been key for Chicago with 18 home runs, 62 RBI and a batting average of .265 this season.

Pete Crow-Armstrong leads Chicago in home runs with 27 while driving in 78 runs and slugging .518.

Seiya Suzuki leads the club in homers (27) and runs batted in (85) this season.

Nico Hoerner leads Chicago with a batting average of .293. He’s also hit four home runs with 47 RBI.

Pirates Key Players to Watch

The Pirates’ Burrows (1-4) will make his 15th start of the season.

Reynolds has racked up a team-high 61 runs batted in.

Andrew McCutchen is batting .243 with 16 doubles, 11 home runs and 48 walks.

Isiah Kiner-Falefa paces the Pirates with a team-high batting average of .268.

Tommy Pham has 12 doubles, a triple, five home runs and 32 walks while hitting .263.

Cubs and Pirates Injuries

Cubs: Miguel Amaya: 10 Day IL (Ankle), Mike Soroka: 15 Day IL (Shoulder), Jameson Taillon: 15 Day IL (Calf), Justin Steele: 60 Day IL (Elbow), Eli Morgan: 60 Day IL (Elbow)

Pirates: Tim Mayza: 60 Day IL (Shoulder), Justin Lawrence: 60 Day IL (Elbow), Endy Rodriguez: 60 Day IL (Elbow), Jared Jones: 60 Day IL (Elbow), Enmanuel Valdez: 60 Day IL (Shoulder), Oneil Cruz: 7 Day IL (Concussion)

Cubs vs. Pirates Prediction

Score Prediction: Cubs 5, Pirates 3 Total Prediction: Under 9.5 runs

How to Bet on Cubs vs. Pirates

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