The federal organization has revealed a newly uncovered side effect that may occur when stopping oral cetirizine (Zyrtec) or levocetirizine (Xyzal) after months to years of daily use. According to a new posting, some people who stopped using one or both of the drugs after regular, long-term use experienced "severe itching," also called pruritus. Reported cases were rare but "sometimes serious," with some patients "experiencing widespread, severe itching that required medical intervention."
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As a result, the FDA is now requiring a warning be added to the prescribing information when the medication is offered as a prescription, and will be requesting manufacturers add a warning about the risk to the Drug Facts Label on over-the-counter containers.
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