Fin Smith retains his spot at No 10 after a Man of the Match performance in the shock victory over France, meaning Marcus Smith will continue at full-back.
I rewatched every England line-out vs France to solve the hooker conundrum
Read MorePerhaps the biggest debate will centre on which of the Smiths assumes kicking duties against Scotland.
Chessum joining captain Maro Itoje in the second row will give England a more mobile option on the ground who can make more impact in line-outs.
“The Calcutta Cup is a special fixture, and we are determined to perform to our very best in front of our supporters at Allianz Stadium.”
England XV and replacements to face Scotland
14. Tommy Freeman (Northampton Saints, 17 caps)
12. Henry Slade (Exeter Chiefs, 71 caps)
10. Fin Smith (Northampton Saints, 8 caps)
1. Ellis Genge (Bristol Bears, 68 caps) – vice-captain
3. Will Stuart (Bath Rugby, 47 caps)
5. Ollie Chessum (Leicester Tigers, 25 caps)
7. Ben Earl (Saracens, 39 caps)
Replacements
17. Fin Baxter (Harlequins, 7 caps)
19. George Martin (Leicester Tigers, 21 caps)
21. Ben Curry (Sale Sharks, 8 caps)
23. Elliot Daly (Saracens, 70 caps)
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