NBC Chicago

Illinois’ health department has released new vaccine guidance for the fall respiratory virus season, aiming to quell “disruption and confusi...

The trial of Ryan Wesley Routh came to a dramatic end Tuesday when he tried to stab himself in the neck with a pen after a Florida jury foun...

I have tried dozens of Italian beef sandwiches in my two decades writing about Chicago food.By far, one of the best I’ve sampled is foun...

One of the most popular roller coasters at Six Flags Great America in Gurnee is back open for business after being shut down for month than...

What to KnowPresident Donald Trump addressed the United Nations General Assembly this morning, delivering remarks on global leadership as re...

If you’ve bought cans of Poppi, a pre-biotic soda brand, over the past few years, you could be entitled to a payout as part of a $8.9 millio...

Four Illinois universities have been named among the 100 best in the country, with two making the top 10, according to the latest ranking fr...

NBA YoungBoy’s Chicago concert at the United Center this week was abruptly canceled by the venue, days before the rapper was set to take the...

Long lines and thousands of buns, dogs and squirts of mustard are expected at The Wieners Circle Tuesday, with the iconic Chicago restaurant...

An Illinois resident has become seriously ill with a tick-borne virus that has never been detected in Illinois before.While the Illinois...

What to KnowPresident Donald Trump today signed an executive order designating antifa, a decentralized set of extreme left-wing groups, as a...

Cook County property owners are still waiting for their second installment tax bills months after they’re typically mailed out in the summer...

A onetime writer for FX’s hit show “The Bear” was taken off a New York City commuter train in handcuffs in a dispute over how he was sitting...

The Chicago Cubs are off Monday, but they can still take a step toward securing home-field advantage in the first round of the playoffs....

In the wake of a highly hyped, late afternoon news conference at the White House where President Donald Trump linked autism spectrum disorde...

Prominent Catholic leaders have urged the Archdiocese of Chicago to reconsider honoring U.S. Sen. Dick Durbin later this fall.Durbin is...

A group of Uptown residents are making an effort to prevent the closure of a hospital that pared down critical services after its removal as...

Officials have discovered a highly invasive plant spreading in the Midwest and issued a warning. The Michigan Department of Natural Reso...

The Bank of America Chicago Marathon course has been known as a destination for record-breaking achievements. Having been the site of wo...

The Department of Homeland Security has addressed rumors on the future of a suburban immigration facility closing following days of protests...

Kara Lawson helped the U.S. women’s basketball team win an Olympic gold medal as a player 17 years ago. Now she’ll have a chance to lead it...

What to KnowPresident Donald Trump praised Charlie Kirk as a “great American hero” and “martyr” for freedom as the president and other promi...

Costco has issued a recall for its Kirkland Signature brand Ahi Wasabi Tuna Poke due to potential listeria contamination, according to a not...

Happy fall, y’all! The autumnal equinox will officially usher in astronomical fall Monday afternoon, with 12 hours and nine minutes of d...

Chicago police say a 20-year-old man has died after he was shot and crashed his vehicle in the East Side neighborhood Sunday morning.Pol...