I have some good news and some bad news. The bad news is that this spring and summer allergy season is set to be long and painful. Warmer temperatures across the nation mean plants are starting to grow earlier, increasing the time pollen can circulate in the air, according to the Asthma and Allergy Foundation of America. Folks from Boise, Idaho, to Lakeland, Florida, are going to face super high pollen counts, which means allergies are about to wreak havoc. The good news is that there are solutions you can turn to for relief, such as common antihistamines like Zyrtec and Claritin.
An unfortunate reality, though, is that traditional over-the-counter medicines can actually stop working.
"With daily antihistamines, some patients develop tolerance over time and find they just stop working as well," Dr. Manan Shah, MD, a practicing ENT and allergist at Wyndly Health, tells Parade. "There's also research that shows that while antihistamines help with allergy symptoms, they can lead to weight gain, brain fog, fatigue, and even dementia."
"The issue is that antihistamines only manage symptoms," he continues. "They never address why your body is overreacting in the first place."
Unfortunately, my husband was one of those folks. In 2023, he found himself taking antihistamines daily with very little result. His eyes were constantly pooling, and I genuinely thought I was going to go mad with the constant sniffling. After getting fed up with it himself, he began researching and found a combination that promised to get the job done: turmeric, quercetin, and bromelain. With nothing to lose, he bought a bottle at our local Walgreens and began taking it daily.
It's been three years, and he hasn't touched an antihistamine since.
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You don't have to take my word for it. Shah explains that the combination naturally mimics what antihistamines do synthetically.
"Quercetin is a natural mast cell stabilizer—it helps prevent your cells from releasing histamine in the first place, which is actually working upstream of where most antihistamines kick in," he explains. "Turmeric's active compound, curcumin, is a potent anti-inflammatory, and since allergies are fundamentally an inflammatory response, that combination can be really effective for certain people."
And to be fair, it really isn't a cure-all for everyone.
"The reason it works dramatically for some and not others comes down to severity, individual biochemistry, and absorption—curcumin is notoriously hard for the body to absorb without black pepper or a fat source," he adds. "For someone with mild allergies and a lot of underlying inflammation, this combo might be a game-changer."
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What Can You Do to Get Ahead of the 2026 Allergy Season?
The truth is, learning what works for your body is key, and the timing of when you do it is everything.
"Whatever works for you—whether that's a quercetin supplement, a nasal steroid, or antihistamines—start it now, before peak season," advises Shah. "These all work best when they're already in your system before pollen counts spike. The biggest mistake I see is people waiting until they're miserable."
Shah also recommends layering treatments as well; adding things like nasal saline rinses and putting HEPA filters in the bedroom can help attack the issue from all angles. The truest solution, though, is slightly more involved.
"To fix the root cause, you need to use allergy immunotherapy. This treatment trains your body to stop having allergy symptoms when exposed to allergy triggers," he claims. "If you're someone who dreads allergy season every year, it's worth looking into immunotherapy. It's the only treatment that actually retrains your immune system to stop overreacting. Supplements and medications can cover up symptoms, but only immunotherapy can be a long-term fix."
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