The Chicago Cubs (72-54) are favorites (-142) on the moneyline when they take on the Milwaukee Brewers (79-47) Thursday at 2:20 p.m. ET, live on MLB Network, MARQ, and FDSWI.
Chicago’s Shota Imanaga gets the start, and he’ll go against Milwaukee’s Quinn Priester.
Cubs vs. Brewers Odds
Cubs odds to win: -142 Brewers odds to win: +119 Spread: Cubs -1.5 Total: 7 runsCubs vs. Brewers Promo Codes
Game Time and Information
Date: Thursday, August 21, 2025 Time: 2:20 p.m. ET TV: MLB Network, MARQ, and FDSWIWho Will Win Cubs vs. Brewers?
Cubs and Brewers Betting Trends
The Cubs are 57-32 in games they were listed as the moneyline favorite (winning 64% of those games).
Chicago has a 40-19 record (winning 67.8% of its games) when it has played as moneyline favorites of -142 or shorter.
The Brewers have won 31, or 53.4%, of the 58 games they’ve played as underdogs this season.
This season, Milwaukee has won nine of its 22 games, or 40.9%, when it’s the underdog by at least +119 on the moneyline.
In the 126 games in which bookmakers have set an over/under for the Cubs, they have combined with opponents to go over the total 59 times (59-61-6).
So far this season, the Brewers and their opponents have hit the over in 59 of their 126 games with a total.
Cubs Stats & Insights
The Cubs have the No. 7 offense in baseball scoring five runs per game (624 total runs).
Chicago ranks seventh in baseball with 172 home runs. They average 1.4 per game.
The Cubs have the 11th-ranked batting average in the majors (.250).
Chicago’s batters strike out 7.7 times per game, the fourth-fewest strikeouts in MLB.
The pitching staff for the Cubs has a collective 7.7 K/9, the third-worst in MLB.
Chicago’s 3.82 team ERA ranks 11th among all MLB pitching staffs.
Brewers Stats & Insights
The Brewers have scored 650 runs this season, which ranks second in MLB.
Milwaukee’s 135 home runs rank 18th in Major League Baseball.
The Brewers rank second in MLB with a .258 team batting average.
Milwaukee ranks eighth in MLB in strikeouts per game with an average of 7.9 Ks per contest.
The Brewers average 8.8 strikeouts per nine innings as a pitching staff, seventh-most in the majors.
Milwaukee has pitched to a 3.58 ERA this season, which ranks second in baseball.
Cubs Key Players to Watch
Imanaga gets the start for the Cubs, his 19th of the season. He is 8-5 with a 3.06 ERA and 85 strikeouts in 103 2/3 innings pitched.
Kyle Tucker has been key for Chicago with 18 home runs, 62 RBI and a batting average of .261 this season.
Pete Crow-Armstrong leads Chicago in home runs with 27 while driving in 79 runs and slugging .516.
Seiya Suzuki leads the club in homers (27) and runs batted in (86) this season.
Nico Hoerner leads Chicago with a .291 batting average. He’s also hit four homers and has 49 RBI.
Brewers Key Players to Watch
The Brewers will hand the ball to Priester (11-2) for his 19th start of the season.
Christian Yelich paces the Brewers with 26 home runs and 87 runs batted in.
William Contreras is batting .260 with 22 doubles, 13 home runs and 70 walks.
Brice Turang is hitting .279 with 23 doubles, 13 home runs and 46 walks.
Sal Frelick is batting .298 to pace his team.
Cubs and Brewers Injuries
Cubs: Miguel Amaya: 10 Day IL (Ankle), Mike Soroka: 15 Day IL (Shoulder), Justin Steele: 60 Day IL (Elbow), Eli Morgan: 60 Day IL (Elbow), Cade Horton: day-to-day (Finger)
Brewers: Jackson Chourio: 10 Day IL (Hamstring), Jake Bauers: 10 Day IL (Shoulder), Rhys Hoskins: 10 Day IL (Thumb), Logan Henderson: 15 Day IL (Elbow), Rob Zastryzny: 15 Day IL (Ribs), D.L. Hall: 15 Day IL (Oblique), Robert Gasser: 60 Day IL (Elbow), Garrett Mitchell: 60 Day IL (Oblique), Connor Thomas: 60 Day IL (Elbow), Jordan Montgomery: 60 Day IL (Elbow)
Cubs vs. Brewers Prediction
Score Prediction: Cubs 5, Brewers 4 Total Prediction: Over 7 runsHow to Bet on Cubs vs. Brewers
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