Study decodes early insights on how bird flu crosses species barrier ...Middle East

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Study decodes early insights on how bird flu crosses species barrier
New Delhi, Aug 19 (IANS) Amid the rising frequency of bird flu infections in mammals and the recent H5N1 strain infection of dairy cows in the US, a new study on Monday decoded how the virus crosses the species barrier to affect mammals and humans. The study by EMBL Grenoble in France shows how avian influenza can change to reproduce in mammalian cells. The viral polymerase enzyme, which is in charge of replication, and the host cell protein ANP32, which controls it, are the main subjects of this study. Cross-species transmission is often inhibited by differences in the ANP32 proteins between birds and mammals; however, viral polymerase mutations can get past this barrier and perhaps cause i

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