The 49ers defense could have gotten off the field if not for the penalty.

It didn’t take long for the Valley’s own Brock Purdy to get on the board with a San Francisco 49ers touchdown against the Cardinals in his t...

Deommodore Lenoir is good to go for the 49ers today against the Arizona Cardinals.Lenoir was listed as questionable Friday with a calf inju...

GLENDALE — Arizona Cardinals defensive lineman Walter Nolen III and cornerback Max Melton are officially active for Sunday’s game against t...

SANTA CLARA, Calif. (AP) — Quarterback Brock Purdy will return to the starting lineup for the San Francisco 49ers this week after missing th...

Target these two road favorites in Week 11 NFL betting.

The 49ers rewarded defensive end Clelin Ferrell by signing him to the 53-man roster Saturday and flexed cornerback Eli Apple from the practi...

Cardinals left tackle Paris Johnson Jr. said he’s never seen anything like it.The 49ers have.Arizona couldn’t practice to start the week....

GLENDALE, Ariz. – Linebacker Tatum Bethune quickly nixed any comparisons between Arizona Cardinals tight end Trey McBride and 49ers counterp...

With a burst of confetti and an official jersey swap, the University of the Pacific (UOP) is now the official higher education partner of th...

The Arizona Cardinals (3-6) hit the field on Sunday at 4:05 p.m. ET at State Farm Stadium against the San Francisco 49ers (6-4). Below, we...

SANTA CLARA — Kyle Shanahan isn’t one to shower his players with undue praise, but where Mac Jones is concerned he was willing to make an ex...

TEMPE — Arizona Cardinals cornerback Will Johnson, right tackle Jonah Williams, pass rusher Baron Browning and safety Dadrion “Rabbit” Taylo...

SANTA CLARA — Brian Robinson Jr. is used to waiting his turn. First it was Najee Harris at Alabama until Robinson became the primary ballcar...

49ers quarterback Brock Purdy has been out for such a long time with a toe injury that some have wondered if surgery was needed.