Getting to the core of HIV replication ...Middle East

Mechanism found for how HIV-1 virus imports nucleotides into its core that fuel DNA synthesis, a key step in its replication. Supercomputer molecular dynamics simulations helped test translocation and free energy calculations. Research supported by the NSF-funded XSEDE through TACC Stampede2 and PSC Bridges. HIV-1 capsid research provides potential for new drug targets for therapeutic development such as improved anti-retroviral drugs.

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