In an exclusive with People, the actor doesn't give a clear starting timeline of when his medical issues all began. He details it having started almost seven years ago with "a cascade of autoimmune-related illnesses" that affected his skin, thyroid, eyes, lungs, and digestive system. Amid the chronic pain, Manganiello also reveals having had a "life-saving organ amputation."
He turned to "shamans, pagan rituals, ancient myths, long-lost family records," as well as changing his own spirituality. Amid his research, the Spider-Man actor discovers his ancestor survived the Armenian genocide and battled with chronic illness.
Amid his own health battle, the actor told People with was the "most brutally difficult" time of his life and wouldn't wish it on his worst enemy. Despite this, he also called it his greatest adventure and hopes his memoir will help others dealing with chronis illness.
Based on Manganiello's reported timeline, he was married toSofia Vergara at the time before splitting in 2024. Reports cited Vergara not wanting any more children as a reason for the breakup. Manganiello is currently engaged to Catlin O’Connor, with the actor's last roles having been in One Piece, and will star in Army of the Dead: Lost Vegas.
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