The 49ers head to top-seeded Seattle next weekend for an NFC divisional playoff game. The NFC West rivals split the season series.
Purdy had two passes intercepted in this one by All-Pro cornerback Quinyon Mitchell, but the Eagles scored just three points off the turnovers.
The Eagles — who won a Super Bowl on a trick play — were foiled by one when Jennings was pitched the ball and rolled right and hit McCaffery on a 29-yard touchdown. The score on the first play of the fourth quarter gave the 49ers a 17-16 lead.
Philadelphia was again doomed by a lethargic offensive effort that cost it a shot at a repeat championship. Super Bowl MVP Jalen Hurts threw for only 168 yards and a touchdown and the Eagles failed to build off a 13-10 halftime lead by totaling only 36 total yards in the third quarter on 16 plays.
Hurts was incomplete on a last-gasp fourth-and-11 attempt with 43 seconds left that ended their final drive.
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