It was confirmed earlier in the year that the show would be wrapping up for a third time, with current producers Amazon MGM Media deciding not to renew beyond their 460 episode commission.
"Once again, we will be resting the residents of Ramsay Street on a hopeful note, with some tantalising possibilities for a future chapter.”
Pictures from the episode airing on 1st December show Holly Hoyland (Lucinda Armstrong-Hall) having a heart-to-heart with dad Karl Kennedy (Alan Fletcher) and his wife Susan (Jackie Woodburne).
What are they discussing?
In the following instalment, a number of old residents make their way back to Melbourne, and head out for a trip to the hills with Shane.
Here's a look at everyone we know to be returning, with more to be confirmed, and what we know about their comebacks.
1. Shane Ramsay (Peter O'Brien)
Max doesn't look particularly pleased, and later, joins Karl and Nicolette Stone (Hannah Monson) in putting more 'Fight the Freeway' banners on the cul de sac.
2. Sam Kratz (Richard Grieve)
In the new snaps he's seen chatting with Shane, Karl, Susan and Max in the Kennedy kitchen. After a few smiles, the group's mood soon changes when they get down to business.
Is he the one behind the redevelopment?
3. Annalise Hartman (Kimberley Davies)
Whatever news they break causes Susan to break down in Karl's arms. And it seems the two aren't given a welcome reception by another old face...
4. Sue Parker (Kate Gorman)
However, after discovering she'd be quids in from the sale of her home, she seemed more on board.
Could she have a change of heart after seeing the impact it will have on everyone?
5. Mackenzie Hargreaves (Georgie Stone)
Mack can be seen accompanying a number of residents on a trip to the countryside, which seems to be organised by Shane.
6. Haz Devkar (Shiv Palekar)
Haz is back too – cosied up with Mackenzie on their chilly trip away from the suburbs. They seem in good spirits, while the Varga-Murphys and Kennedys don't look as enthusiastic.
Jane can be seen holding a brochure again, could it be that Shane is proposing to build an alternative housing development?
7. Lucas Fitzgerald (Scott Major)
After selling up to Max, it seemed we'd never see him again. However, donning his infamous biker jacket, Lucas joins everyone on Shane's recce.
8. Levi Canning (Richie Morris)
It's been over three years since we last saw him, in what was then deemed the 'final' ever episode. He confessed his love to Freya Wozniak (Phoebe Roberts), and as explained when the show returned the next year, later moved to her childhood home of Echuca.
Why he's decided to support Ramsay Street in its hour of need remains to be seen – as he has no family ties to the destination anymore.
9. Remi Varga-Murphy (Naomi Rukavina)
In a move to facilitate actress Naomi's maternity leave, Remi left for a break in Apollo Bay, still struggling to remember her married life.
Will she ever remember her old life, and will JJ be ok?
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Neighbours is available to stream on Amazon Prime Video.
Check out more of our Soaps coverage or visit our TV Guide and Streaming Guide to find out what's on. For more from the biggest stars in TV, listen to The Radio Times Podcast.
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