The San Francisco Giants (64-68) will vie for their fourth straight victory when they host the Chicago Cubs (76-56) on Thursday at 3:45 p.m. ET on NBCS-BA and MARQ. The Cubs are listed as -130 favorites to stop the streak, while the Giants are +110 underdogs to keep their momentum.
Chicago’s Shota Imanaga gets the start, and he’ll go against San Francisco’s Logan Webb.
Cubs vs. Giants Odds
Cubs odds to win: -130 Giants odds to win: +110 Spread: Cubs -1.5 Total: 8.5 runsCubs vs. Giants Promo Codes
Game Time and Information
Date: Thursday, August 28, 2025 Time: 3:45 p.m. ET TV: NBCS-BA and MARQWho Will Win Cubs vs. Giants?
Cubs and Giants Betting Trends
The Cubs have won 63.8% of the games this season when they were the moneyline favorite (60-34).
When playing as moneyline favorites with odds of -130 or shorter, Chicago has a record of 49-24 (67.1%).
The Giants have been underdogs in 55 games this season and won 26 (47.3%) of those contests.
San Francisco has entered 36 games this season as the underdog by +110 or more and is 16-20 in those contests.
The Cubs have played in 132 games with set over/under, and have combined with opponents to go over the total 61 times (61-65-6).
So far this season, the Giants and their opponents have hit the over in 59 of their 132 games with a total.
Cubs Stats & Insights
The Cubs are the seventh-highest scoring team in the majors, averaging 4.9 runs per game (650 total).
Chicago ranks seventh-best in baseball with 178 total home runs.
The Cubs rank 13th in MLB with a .249 batting average.
Chicago’s hitters strike out 7.8 times per game, the fourth-fewest strikeouts in baseball.
The Cubs pitching staff is 27th in the majors with a collective 7.8 strikeouts per nine innings.
Chicago has the seventh-ranked team ERA across all MLB pitching staffs (3.77).
Giants Stats & Insights
The Giants have scored 535 runs (4.1 per game) this season, which ranks 25th in MLB.
San Francisco’s 130 home runs rank 23rd in Major League Baseball.
The Giants have a team batting average of just .231 this season, which ranks 28th among MLB teams.
San Francisco ranks 19th in MLB in strikeouts per game with an average of 8.7 Ks per contest.
The Giants strike out 8.5 batters per nine innings as a pitching staff, 13th in MLB.
San Francisco pitchers have a combined ERA of 3.73 ERA this year, sixth-best in baseball.
Cubs Key Players to Watch
Imanaga (8-6 with a 3.03 ERA and 90 strikeouts in 110 2/3 innings pitched) gets the start for the Cubs, his 20th of the season.
Kyle Tucker is batting .262 with 21 home runs and 69 RBI for Chicago this season.
Pete Crow-Armstrong’s 28 home runs are most among Chicago batters. He’s driven in 82 runs this season while slugging .510.
Nico Hoerner is batting .288 to lead Chicago, while adding four homers and 50 runs batted in this season.
Seiya Suzuki is a key run producer for Chicago with a .244 average, 27 homers and 87 RBI.
Giants Key Players to Watch
Webb (12-9) will take to the mound for the Giants and make his 28th start of the season.
Rafael Devers leads the Giants with 25 home runs and 84 runs batted in.
Jung Hoo Lee is batting .259 with 29 doubles, 10 triples, seven home runs and 41 walks.
Willy Adames is hitting .223 with 18 doubles, two triples, 22 home runs and 63 walks.
Heliot Ramos is hitting .264 to pace his team.
Cubs and Giants Injuries
Cubs: Miguel Amaya: 10 Day IL (Ankle), Ryan Brasier: 15 Day IL (Groin), Mike Soroka: 15 Day IL (Shoulder), Jameson Taillon: 15 Day IL (Groin), Justin Steele: 60 Day IL (Elbow), Eli Morgan: 60 Day IL (Elbow)
Giants: Jerar Encarnación: 10 Day IL (Hamstring), Landen Roupp: 15 Day IL (Knee), Randy Rodriguez: 15 Day IL (Elbow), Tom Murphy: 60 Day IL (Back), Erik Miller: 60 Day IL (Elbow)
Cubs vs. Giants Prediction
Score Prediction: Cubs 5, Giants 4 Total Prediction: Under 8.5 runsHow to Bet on Cubs vs. Giants
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