Barrymore sat down with Valerie Bertinelli, who often appears on the show, Dr. Kameelah Phillips, an obstetrician-gynecologist, and Inside Edition's Alison Hall to talk about breast cancer and early screening when she mentioned her past procedure.
Hall recounted her experience being diagnosed with breast cancer late last year after doing research for a story, with Phillips then emphasizing the necessity of early screening.
The comment was a rare reference to Barrymore's breast reduction surgery at the age of 17.
Barrymore previously spoke about her decision to get breast reduction surgery in a conversation with the New York Daily News in 1998, via E! News, with the 50 First Dates actress saying, "There's something very awkward about women and their breasts because men look at them so much. When they're huge, you become very self-conscious."
A few years ago, Barrymore shared some insight into why she hasn't had any other procedures since then, telling People, "I have a highly addictive personality, so I worry I'd continue to chase it, get this and that done."
Next: Drew Barrymore Reveals Daughters' Reactions to Watching Her in Scream for the First Time
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