Station Science Top News: Oct. 4, 2024 ...Middle East

Engineered heart tissues in space showed impairments that led to increased arrhythmias and loss of muscle strength, changes similar to cardiac aging. This finding suggests that the engineered tissues, essentially an automated heart-on-a-chip platform, can be used to study cardiac issues in space and aging-related cardiovascular disease on Earth. Microgravity exposure is known to cause changes in cardiovascular function similar to those seen with aging on Earth. Engineered Heart Tissues assessed these changes using 3D cultured cardiac muscle tissue. The 3D cultures, grown with special scaffolds and derived from human cells, are better at reproducing the behavior of actual tissues than

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