Study sheds light on rare genetic variants that increase risk for lung cancer ...Middle East

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Study sheds light on rare genetic variants that increase risk for lung cancer
Lung cancer is the leading cause of cancer death. While the risk for this disease can be influenced by environmental and lifestyle factors like smoking, studies estimate that 18 per cent of lung cancer cases are due to inherited genetic variants. New research led by Baylor College of Medicine investigates how genetic variants contribute to increased risk of lung cancer. The researchers performed whole-exome sequencing on germline (inherited) DNA from eight large-scale datasets, including 1,045 patients with a family history of lung cancer or early-onset cancer. Those groups are more likely to harbour genetic risk variants. The analysis also included 885 control cases.

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