The extended international break may be over but its impact will be felt in the Premier League over the next few weeks.
A change to the FIFA schedule meant the September and October international windows were combined into one three-week break, with many national teams playing four games in less than a fortnight.
Unsurprisingly, injuries have piled up and top-flight teams head into this weekend's fixtures without many of their star players.
That's a problem facing Fantasy Premier League managers as well, as they click back into gear after three weeks without having to worry about their squad.
Fears have been eased about an injury to Manchester City striker Erling Haaland – to the relief of many – but should FPL managers prepare to be without?
With the help of Squawka and the latest announcements in press conferences, Radio Times has all broken down all the Premier League injuries ahead of gameweek 6.
Out
William Saliba (lower back injury)Christos Tzolis (thigh injury)Doubtful
Ezri Konsa (thigh injury)Cristhian Mosquera (thigh injury)Ben White (groin/hip/pelvic injury)Max Dowman (other)Kai Havertz (thigh injury)Back in training
Declan Rice (thigh injury)Aston Villa injury latest
Out
Amadou Onana (knee injury)Ian Maatsen (ankle/foot injury)Leon Goretzka (knee injury)Pau Torres (thigh injury)Marco Bizot (lower back injury)Brian Madjo (ankle/foot injury)Doubtful
Alysson (other)Back in training
Matty Cash (thigh injury)Bournemouth injury latest
Out
Alex Scott (thigh injury)Eli Kroupi (ankle/foot injury)Julian Araujo (thigh injury)Justin Kluivert (other)Veljko Milosavljevic (knee injury)Amine Adli (calf/shin/heel injury)Out
Mathias Jensen (other)Joshua Dasilva (thigh injury)Antoni Milambo (knee injury)Nathan Collins (calf/shin/heel injury)Sepp van den Berg (groin/hip/pelvic injury)Kaye Furo (ankle/foot injury)Doubtful
Mikkel Damsgaard (ankle/foot injury)Dango Ouattara (illness)Brighton injury latest
Out
Stefanos Tzimas (knee injury)Yankuba Minteh (calf/shin/heel injury)Kaoru Mitoma (thigh injury)Jack Hinshelwood (other)Mats Wieffer (knee injury)Femi Azeez (thigh injury)Zadok Yohanna (other)Evan Ferguson (ankle/foot injury)Doubtful
Lewis Dunk (upper back/neck injury)Pascal Struijk (thigh injury)Yasin Ayari (illness)Out
Joao Pedro (knee injury)Marco Palestra (other)Moises Caicedo (calf/shin/heel injury)Emmanuel Emegha (other)Reece James (thigh injury)Doubtful
Jamie Gittens (ankle/foot injury)Back in training
Cole Palmer (groin/hip/pelvic injury)Coventry City injury latest
Out
Haji Wright (thigh injury)Taiwo Awoniyi (suspended)Kaine Kesler-Hayden (thigh injury)Josh Eccles (calf/shin/heel injury)Luke Woolfenden (knee injury)Aurele Amenda (calf/shin/heel injury)Doubtful
Milan van Ewijk (thigh injury)Out
Chadi Riad (knee injury)Axel Disasi (suspended)Jean-Philippe Mateta (thigh injury)Dean Henderson (ankle/foot injury)Doubtful
Anan Khalaili (thigh injury)Takehiro Tomiyasu (calf/shin/heel injury)Everton injury latest
Out
Merlin Rohl (other)Doubtful
Vitalii Mykolenko (other)Back in training
Christian Norgaard (other)Out
Tom Cairney (knee injury)Kenny Tete (head/face injury)Hull City injury latest
Out
Eliot Matazo (knee injury)Jack Butland (arm/elbow injury)Darko Gyabi (groin/hip/pelvic injury)Ilyas Ansah (lower back injury)Charlie Hughes (groin/hip/pelvic injury)Hidemasa Morita (groin/hip/pelvic injury)Nobel Mendy (head/face injury)Back in training
Brooke Norton-Cuffy (groin/hip/pelvic injury)Matt Targett (ankle/foot injury)Elliot Stroud (illness)Out
Issahaku Fatawu (suspended)Jack Taylor (knee injury)Leeds United injury latest
Out
Mateo Joseph (knee injury)Joe Rodon (thigh injury)Harry Wilson (thigh injury)Doubtful
Jean-Matteo Bahoya (ankle/foot injury)Out
Hugo Ekitike (calf/shin/heel injury)Conor Bradley (knee injury)Giovanni Leoni (knee injury)Federico Chiesa (lower back injury)Doubtful
Alexander Isak (thigh injury)Jeremy Jacquet (thigh injury)Cody Gakpo (ankle/foot injury)Man City injury latest
Out
Phil Foden (suspended)Doubtful
Antoine Semenyo (ankle/foot injury)Nico O'Reilly (other)Man Utd injury latest
Out
Matthijs de Ligt (lower back injury)Manuel Ugarte (knee injury)Doubtful
Karl Darlow (other)Kobbie Mainoo (other)Amad Diallo (ankle/foot injury)Benjamin Sesko (calf/shin/heel injury)Tom Heaton (thigh injury)Marcus Rashford (groin/hip/pelvic injury)Patrick Dorgu (thigh injury)Noussair Mazraoui (lower back injury)Out
Ewen Jaouen (thigh injury)Valentino Livramento (other)Doubtful
Jacob Ramsey (thigh injury)Anthony Elanga (thigh injury)Amar Dedic (thigh injury)Sean Steur (other)Matias Fernandez-Pardo (other)Dan Burn (ankle/foot injury)William Osula (ankle/foot injury)Back in training
Nicolas Gonzalez (head/face injury)Joelinton (thigh injury)Lewis Miley (other)Nottingham Forest injury latest
Out
Nikola Milenkovic (thigh injury)Nicolo Savona (knee injury)Out
Romaine Mundle (knee injury)Mouhamadou Habib Diarra (thigh injury)Reinildo (suspended)Dan Ballard (thigh injury)Doubtful
Brian Brobbey (thigh injury)Noah Sadiki (other)Tottenham injury latest
Out
Xavi Simons (knee injury)Wilson Odobert (knee injury)Mykhailo Mudryk (ankle/foot injury)Pedro Porro (thigh injury)Dejan Kulusevski (knee injury)Doubtful
Jan Paul van Hecke (ankle/foot injury)Back in training
Micky van de Ven (wrist/hand injury)Check out more of our Sport coverage or visit our TV Guide and Streaming Guide to find out what's on. For more TV recommendations and reviews, listen to The Radio Times Podcast.
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