Every Star Who's Admitted To Using Ozempic, WeGovy and Other Weight Loss Drugs (So Far) ...Saudi Arabia

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Every Star Whos Admitted To Using Ozempic, WeGovy and Other Weight Loss Drugs (So Far)

Once used exclusively for managing diabetes, celebrities' use of weight loss medications like Ozempic, Mounjaro, Wegovy, Zepbound and more thrust the drugs into the mainstream.

Despite their ubiquity, not every star who's used them has had positive experiences in their efforts to speed up their slimming down, with several celebrities lamenting the nausea they suffered on the drugs, others saying they simply didn't work for them and at least one star admitting they were distraught at constipation they suffered while on Ozempic.

    Other stars who were rumored to use the drugs (including Kim Kardashian when she had to fit into Marilyn Monroe's gown for the Met Gala) have vehemently denied relying on medications for their weight loss, instead insisting that they got their f**cking ass up and worked.

    Whether there's a financial incentive to their endorsements (and several of them are paid spokespersons for weight loss drugs, because even while promoting the idea that thin is in, they still want their wallets to be fat), or they're just trying to promote a more honest culture around body image and setting more realistic standards for women, these celebs have all spoken publicly about using Ozempic and its ilk to drop pounds.

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    Celebrities on Ozempic and Other Weight Loss Drugs

    Anthony Anderson

    Anthony Anderson in January 2024

    Kevin Winter/Getty Images

    Black-ish star Anthony Anderson, who has type 2 diabetes, said the Ozempic fad has negatively impacted patients who need semaglutide medications for health reasons.

    "I will say this," he told PEOPLE. "It's creating a shortage for those of us who need the medicine that we need and not for weight loss issues, but for our health."

    Related: How Much Weight Can You Expect to Lose On Ozempic?

    Remi Bader

    Remi Bader in February 2026

    Photo by Dave Benett on Getty Images

    Influencer Remi Baderrevealed on the Not Skinny But Not Fat podcast that her doctors told her in early 2020 that she needed to go on Ozempic for health reasons: Bader recalled that she was pre-diabetic, overweight and had insulin resistance. However, the medication didn't work out well for her in the long run.

    "I had a lot of mixed feelings [about using Ozempic]," she said. "A few months later I went off it and got into the bad binging."

    Bader sought treatment for binge eating afterward and said she gained "double the weight back" after stopping her Ozempic use. "I saw a doctor and they were like, it's 100% because I went on Ozempic," she said. "It was making me think I wasn't hungry for so long, I lost some weight. I didn't wanna be obsessed with being on it long-term. I was like, 'I bet the second I got off I'm gonna get starving again.' I did, and my binging got so much worse. So then I kind of blamed Ozempic."

    She eventually underwent bariatric surgery, she revealed to Self in 2025, and was pictured in February 2026 looking more svelte than ever.

    Related: What Happens When You Stop Taking Ozempic

    Charles Barkley

    Charles Barkley in September 2024

    Photo by Derek White on Getty Images

    NBA legend Charles Barkley revealed that he used Mounjaro to drop 65 pounds, starting his weight loss journey at 355.

    "There’s so many different ways to lose weight," he said on his King James CNN show. "There’s no shoe size that fits all. But I gained 105 pounds ... and a friend of mine says, 'Yo, man, I want you to go to this doctor,' because I can’t eat less and work out enough to lose 100 pounds. And [the doctor] says, 'Try this drug.' And I started taking Mounjaro. And I have lost 65 pounds. I started my journey at 355 pounds. I played at 250. I’m down to 285."

    He reportedly had to stop using it temporarily due to shortages, leading him to gain 12 pounds back, but said he wanted to go back on to lose another 15 pounds.

    Kathy Bates

    Kathy Bates in January 2026

    Photo by Robin L Marshall on Getty Images

    Kathy Bates went on Ozempic for her diabetes, which contributed in part to her 100-pound weight loss, but wasn't the only factor.

    "I’ve recently gone on Ozempic and everybody said, ‘Oh, she did it with Ozempic,’ but that’s not true," Bates said on The Drew Barrymore Show. "I started doing that about a year ago for my diabetes and that’s helped me lose the last 15 pounds or so. But even with the Ozempic, I still have to pay attention [to my diet].”

    Boy George

    Boy George in August 2023

    Rick Kern/Getty Images

    Boy Georgewrote in his memoir Karma (via PEOPLE) that he tried both Ozempic and Mounjaro to lose weight after struggling for years.

    Noting that he also had a tummy tuck, he called semaglutide medications "wonder drugs" and said "anyone who was fat last year and is now skinny" was likely using them.

    Bunnie XO

    Bunnie XO in February 2026

    Photo by Taylor Hill on Getty Images

    Bunnie XO, podcaster and better half to singer and rapper Jelly Roll, said that being on weight loss drugs actually gave her "suicidal ideation" in December 2025.

    “Both my parents had diabetes. So my insulin numbers are really crazy and my body just cannot tolerate it,” she explained to PEOPLE, adding, “I prided myself on the fact that I only had anxiety. I never had depression. So when you get slammed with suicidal ideation and visions and just, oh, it was horrific.”

    Thankfully, after what she said was a "rough month" on the drug, she's OK now.

    Related: Bunnie Xo Details Sex Life Struggles When Jelly Roll Weighed 500 Pounds

    Kandi Burruss

    Kandi Burruss in February 2026

    Photo by Bruce Glikas on Getty Images

    Singer, songwriter and Bravo star Kandi Burruss said that she tried a weight loss drug with no success, which led her mental health to suffer.

    “Last year, I tried it. I saw so many people who were trying it and losing weight. So I was like, ‘OK, I’m going to try this,’" she said on the Page Six Virtual Reali-tea podcast in June 2025. "And I didn’t lose any weight! My doctor was like, ‘I don’t know what the problem is, I’m not seeing this in other people.’"

    "It didn’t curb my appetite," she added. "I know some people are like, ‘Oh, I can’t eat.’ Not me. I was eating appetizers, a regular meal and dessert. It didn’t stop anything for me. It makes you depressed. Realistically, it makes you feel like, ‘What is wrong with me? Why is it not working for me?'"

    Dolores Catania

    Dolores Catania in November 2023

    Bravo/Getty Images

    Real Housewives of New Jerseystar Dolores Cataniatold Andy Cohenon Watch What Happens Live! that she was using Ozempic, quipping, "I wasn't going to come to [the] reunion looking bigger than anyone else, so I got on the bandwagon."

    Related: The Surprising Benefit of Weight Loss Drugs, According to Obesity Doctors

    Savannah Chrisley

    Savannah Chrisley in 2024

    Photo by Chip Somodevilla on Getty Images

    Sure, "celebrity" may be slightly loosely used here, but Savannah Chrisley admitted to losing 25 pounds with a weight loss drug. Still, it took a bit of time to find one that worked for her.

    “I love food,” she explained her Unlocked podcast. “That’s the hard part. So when I’m on the shot and I can’t eat, I’m like, ‘I really love food.’”

    Kelly Clarkson

    Kelly Clarkson in June 2024

    NBC/Getty Images

    After much speculation about her weight loss (which she initially said was a result of walking a lot after moving her show to New York City), Kelly Clarksonadmitted on an episode of her talk show that she used medication because she was pre-diabetic. She said it wasn't Ozempic, but didn't specify the exact drug she used, except that it was "something that aids in helping break down the sugar—obviously my body doesn’t do it right."

    "My doctor chased me for, like, two years, and I was like, ‘No, I’m afraid of it. I already have thyroid problems,’" she recalled. After she had bloodwork turn out badly, however, she agreed to go on medication to regulate her blood sugar, which in turn sparked some of her weight loss. She said at her heaviest she weighed 203 pounds and didn't even recognize herself, but that she was "happy" regardless of her size.

    Related: Ozempic Before and After Pictures

    James Corden

    James Corden in February 2026

    Photo by Ian West - PA Images on Getty Images

    James Corden tried Ozempic, but says it didn't work for him.

    "What I realized was I was like, 'Oh no, nothing about my eating has anything to do with being hungry,'" he explained on his podcast This Life of Mine (via E! News). "All this does is make you feel not hungry. But I am very rarely eating [just because of hunger]."

    Terry Dubrow

    Terry Dubrow in May 2024

    Steve Granitz/Getty Images

    Celebrity plastic surgeon Terry Dubrow tried Ozempic, tellingPage Sixin January 2024, "I thought it was amazing. I didn’t have that much weight to lose. But I wanted to try it because so many of my patients were on it and I wanted to see what it was like when you’re not diabetic and you only have 10 to 15 pounds to lose."

    After going off the drug, he toldE! Newsthat March, "How am I doing off Ozempic? I'm overweight and chubby. There's more to love, but I'll tell you something: I'm off it, but I plan on going back on it when it's appropriate. Like we have a vacation and after that I'll come back. It's like the new Botox ... I love it. It's so good." (Do note that doctors do not recommend weight loss medications for short-term use or for small-scale weight loss.)

    Jennifer Fessler

    Jennifer Fessler in November 2023

    Mindy Small/Getty Images

    Fellow Garden State Real Housewife Jennifer Fesslersaid on Watch What Happens Live in March 2023 that she'd used weight loss medications to lose weight. When pressed if it was Ozempic, she told host Cohen, "You said it, I didn't, but whatever works, here I am."

    That December, she revealed she was hospitalized for an impacted bowel, a side effect of her Ozempic use.

    Harvey Fierstein

    Harvey Fierstein in June 2025

    Photo by Dimitrios Kambouris on Getty Images

    Beloved Broadway legend Harvey Fierstein dropped 120 pounds with Zepbound after hitting 310 pounds during the COVID-19 pandemic.

    “People don’t understand that being fat is not a choice,” Fierstein explained to Page Six. “It’s something that your body is out of whack and this puts your body in whack.”

    "What’s different is what the drug actually does for you, which is: I don’t feel like I’m dieting,” Fierstein said. “I feel like a normal person. I can go and have dinner with friends and not have to eat every piece of bread on the table, and then not go have ice cream when I’ve done with dinner.”

    Stephen Fry

    Stephen Fry in July 2024

    Karwai Tang/Getty Images

    British actor Stephen Fry said he tried Ozempic at the advice of his doctor, but it didn't work out for him.

    "The first week or so, I was thinking, ‘This is astonishing. Not only do I not want to eat, I don't want any alcohol of any kind. This is going to be brilliant,’" he recalled in March 2024. "Then I started feeling sick, and I started getting sicker and sicker and sicker. I was literally throwing up four, five times a day and I thought, ‘I can't do this.’ So that's it."

    Jim Gaffigan

    Jim Gaffigan in November 2025

    Photo by Jamie McCarthy on Getty Images

    After topping 270 pounds, comedian Jim Gaffigan tried Mounjaro and is glad he did.

    "I'm just grateful because it's such a better life," he told PEOPLE, adding, "I almost thought it was kind of odd that people were resistant to talking about it. I don’t think there’s anything wrong with it. There’s people walking around that obviously do not have blonde hair — yet they do. I don’t think that’s weird, either. It’s just whatever gets you through."

    He also touched on his weight loss in his November 2024 special The Skinny.

    Heather Gay

    Heather Gay in November 2023

    Monica Schipper/Getty Images

    Heather Gayof Real Housewives of Salt Lake Citysaid that Ozempic didn't do much for her.

    "I've been on it for a long time, but hadn't really seen much results," she told PEOPLE in November 2023. "And I haven't had massive results, but enough for people to notice, which is great."

    Golnesa "GG" Gharachedaghi

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    Former Shahs of Sunsetstar Golnesa "GG" Gharachedaghiused Ozempic specifically for weight loss.

    "I had to get a lot of steroid injections last year, which caused me to really pack on some weight, and I don't know if it's because I'm 41 years old or I've had a baby," she said in a February 2023 Instagram video. "Whatever it is, I’ve been having a very, very, very hard time getting rid of that weight."

    "When I started semaglutide shots, I was 138 pounds. Now, I’m about 110 pounds," she said. "As you can see, I've lost a little more weight than I was anticipating to lose. I decided I'm only gonna weigh myself on the days of my injections just to document it. And on April 30, I got on the scale and I saw 111 lbs. That’s when I knew, it's time to cut back. That's when I started cutting down on units and going backwards and backwards until finally now, I'm just on maintenance."

    She added, "I encourage it to anybody who's having a hard time losing weight and wants the 'easy route.' Summer's around the corner."

    Related: The Best Exercise for People on Ozempic, According to Obesity Doctors

    Whoopi Goldberg

    Whoopi Goldberg on "The Kelly Clarkson Show" in 2024

    NBC/Getty Images

    In a sitdown onThe Kelly Clarkson Show, The Viewhost Whoopi Goldbergsaid she was using the weight loss drug Mounjaro. "I've lost almost two people [worth of weight]," Goldberg joked, adding, "I am doing that wonderful shot that works for folks who need some help, and it’s been really good for me."

    Related: What It's Like to Take Ozempic, Week by Week

    Jon Gosselin

    Jon Gosselin in April 2024

    Paul Archuleta/Getty Images

    Former Jon & Kate Plus 8star Jon GosselintoldPage Sixthat he lost over 30 pounds since going on Ozempic.

    "You know what's annoying? The regret of not starting it 10 years ago," he said. "I feel amazing! Like, why didn't I do this sooner? Maybe it wasn't the right time."

    "It's really nice because it helped me stop drinking and it helped me get my appetite under control with less eating," he explained. "I was able to really refocus my diet that way, I just focused on consuming what I need to consume in a healthy manner."

    Related: Ozempic vs. Metformin: Similarities, Differences, and How to Know What's Best for You

    Macy Gray

    Macy Gray in March 2025

    Photo by Scott Dudelson on Getty Images

    "I Try" singer Macy Gray revealed on The Surreal Life: Villa of Secrets that her weight loss meds weren't a great experience.

    "Oh, boy my stomach hurts," Macy groaned. "I took Ozempic. I can't go to the bathroom, and I was up all night."

    Chelsea Handler

    Chelsea Handler in January 2024

    Kevin Mazur/Getty Images

    Comedian Chelsea Handlersaid she tried Ozempic after getting it from her "anti-aging doctor."

    "I didn't even know I was on it. She said, 'If you ever want to drop five lbs., this is good,'" Handler recalled on the Call Her Daddy podcast. She said she injected herself with it after a vacation and soon learned a friend of hers also used the medication and complained she was nauseous from it.

    "I'm not on it anymore. That's too irresponsible," she said. "I'm an irresponsible drug user, but I'm not gonna take a diabetic drug. I tried it, and I'm not gonna do that. That's not for me. That's not right for me."

    She added, "I've injected about four or five of my friends with Ozempic because I realized I didn't wanna use it cause it's silly. It's for heavy people. Everyone is on Ozempic. It's gonna backfire, something bad is gonna happen."

    Related: Top Foods to Limit If You're On Ozempic, According to Obesity Doctors

    Sunny Hostin

    Sunny Hostin in July 2024

    Taylor Hill/Getty Images

    Fellow co-host of The View Sunny Hostinrevealed that she began using Mounjaro after gaining weight during the height of the COVID-19 pandemic.

    "During COVID, I gained 40 pounds. All I did was eat," she said onThe View(viaPEOPLE). "I love to cook, and I found out, I love to eat. And I was horrified about the fact that I would have to come out on air. So I also took Mounjaro."

    It had a significant help benefit for Hostin.

    "I found that my cholesterol went up to 200 when I gained the extra weight. I use Mounjaro and my cholesterol is 140 now," she said. "I feel better, I think I look better, and that's what this is about for people."

    Related: The #1 Ozempic Mistake People Make, According to Obesity Doctors

    Margaret Josephs

    Margaret Josephs in February 2026

    Photo by Bruce Glikas on Getty Images

    Margaret Josephsof Real Housewives of New Jerseysaid that menopause made losing weight hard, so she sought help from her doctor, who prescribed Ozempic.

    "It shuts off that food noise, my blood work is great. [Before Ozempic] I couldn’t do anything," she said. "It doesn't matter if I was eating right or exercising. So I don't know why there's any shame in it if it's helpful to people."

    Related: How to Get Prescribed Ozempic for Weight Loss

    Billie Jean King

    Billie Jean King in January 2026

    Photo by Robin Marchant on Getty Images

    Tennis legend Billie Jean King said that her doctor recommended Ozempic to help treat her binge eating disorder.

    “If [weight loss medication] does quiet the voices—if that’s a part of it—now I’m [into] it because that would be really great, because that gets exhausting and tiring," she told Julia Louis-Dreyfus on her Wiser Than Me podcast. "And I don’t want to fight over these things."

    Lauren Manzo

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    RHONJand Manzo'ed With Children star Lauren Manzoused Mounjaro for weight loss but advised about the negative message some of her reality show peers and celebrities send with their use of medications to slim down.

    "I think it's being abused because I see people, Housewives, that are posting and you literally see their ribs, and it's sad because you were already skinny," she explained. "That is a bad thing for somebody like me who has suffered from high blood pressure and anxiety from being super heavy and depression. People that are already 130 pounds and just want to lose 10 more, and they want to stay on it—that, I don't respect."

    Gracie McGraw

    Gracie McGraw in May 2023

    Manny Carabel/Getty Images

    Tim McGrawand Faith Hill's daughter Gracie McGrawsaid she's on Ozempic for health reasons: She has polycystic ovarian syndrome (PCOS), which can cause insulin resistance. She wrote on Instagram (via Page Six) that she switched from Ozempic to a lower dose of Mounjaro to help manage her PCOS symptoms.

    Related: The No. 1 Weight Loss Secret, According to Obesity Doctors

    Tracy Morgan

    Tracy Morgan in November 2023

    Mike Coppola/Getty Images

    Comedian, 30 Rock star and overall treasure Tracy Morganhad a predictably hilarious take on his use of Ozempic.

    "I went and got a prescription, and I got Ozempic," he said on TODAY in August 2023. "I ain't letting it go. It cuts my appetite in half. Now I only eat half a bag of Doritos."

    Elon Musk

    Elon Musk in January 2024

    Anadolu/Getty Images

    In October 2022, the world's richest man, Elon Musk, revealed on X (formerly Twitter) that fasting "and Wegovy" were his keys to weight loss.

    Interestingly, Musk's own Grok chatbot says that President Donald Trump was referring to the Tesla CEO when he made a crack about a "seriously overweight" friend who told him he was taking the "fat shot," to which the former Apprentice host replied, "It's not working." Too bad he couldn't use that chainsaw to cut his calories.

    Rosie O'Donnell

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    Rosie O'Donnell was astounded at the difference Mounjaro made in her weight, documenting her transformation on Instagram.

    "Ok so went shopping to (buy) a comfy lounge wear outfit for my 22 hour flight to australia- was undecided as i cant see myself in this new smaller body," she captioned a photo in August 2025. "Cam n robin took this photo of me in the dressing room — i am shocked im a 12 — #mounjaro is a life saver ?❤️??"

    Kelly Osbourne

    Kelly Osbourne in February 2026

    Photo by Dave Benett on Getty Images

    Kelly Osbourne underwent gastric surgery in 2018 and lost 85 pounds, but gained about 100 pounds and was diagnosed with gestational diabetes during her pregnancy in 2022. After giving birth to son Sid that November, she says she "went a little overboard" losing her baby weight, but denied using Ozempic at the time.

    In May 2025, however, she admitted to at least trying some type of unspecified medication at one point, saying, “I tried probably everything that there is out there, whether it be surgery, medication, diet and exercise. I got my mind where I needed it to be, and everything started to fall into place.”

    Since then, Osbourne has lost even more weight, which she attributed to the grief of losing her father, Ozzy Osbourne, in July 2025.

    Sharon Osbourne

    Sharon Osbourne in February 2026

    Photo by Samir Hussein on Getty Images

    Sharon Osbournesaid she thinks she lost too much weight on Ozempic, but that she doesn't regret using it.

    "You can't stay on it forever. I lost 42 pounds now and it's just—enough," she said on Piers Morgan Uncensored in September 2023. "I didn’t want to go this thin. It just happened."

    Osbourne said the medication made her feel nauseous for about two weeks straight, adding, "You get very thirsty and you don’t eat. That’s why I say you have to keep this stuff away from younger people. They will go berserk on it and it's not right."

    She also noted that she got so thin that her husband Ozzy Osbournebegan calling her "Nancy Reagan."

    Related: How Common Is Nausea on Ozempic?

    Claudia Oshry

    Claudia Oshry in May 2024

    Sarah Kerver/Getty Images

    Internet personalityClaudia Oshrylost 70 pounds on Ozempic, but said her hair was shedding as a side effect of the drug—and that since going off of it, she was hungry all the time.

    Amy Schumer

    Amy Schumer in October 2025

    Photo by XNY/Star Max on Getty Images

    Amy Schumer, who's been open about having liposuction in the past, was just as candid about her use of Ozempic for weight loss—and she didn't love it.

    "I tried it," she said on Watch What Happens Live in June 2023. "I was one of those people that felt so sick and couldn't play with my son. I was so skinny and he's throwing a ball at me and [I couldn't]."

    "I immediately invested [in it] because I knew everyone was going to try it," she said, adding that she gets vexed when celebrities lie about not using weight loss meds to drop pounds. "Everyone has been lying saying, 'Oh smaller portions.' Like shut the f—k up. You are on Ozempic or one of those things or you got work done," she said. "Be real with the people. When I got lipo, I said I got lipo."

    That said, Schumer has had no issues posting and boasting about her 50-poundMounjaro weight loss (and even deleting all her past Instagram photos) after she invested in a company that sells it.

    June "Mama June" Shannon

    June "Mama June" Shannon in May 2025

    Photo by Michael Simon on Getty Images

    After previously undergoing a gastric sleeve surgery documented in her reality show Mama June: From Not to Hot, Mama June Shannongained some of her weight back. She turned to weight loss injections to help her on her weight loss journey and encouraged fans to talk to their physicians to find out what medications or programs can work best for them. She also wants to help patients find lower-cost alternatives for and generic versions of expensive prescriptions.

    Emily Simpson

    Emily Simpson in November 2023

    Mindy Small/Getty Images

    Real Housewives of Orange Countystar Emily Simpsonsaid on Jeff Lewis Live in June 2023 that she got liposuction and used Ozempic for a month at the suggestion of her doctor. She said that after being on the medication, her poor eating habits "went away," adding, "It made me more conscientious of what I was eating and so that was a really great kick start for me."

    Related: Ozempic Butt: Causes, Side Effects, How to Get Rid of It

    Tori Spelling

    Tori Spelling in April 2024

    Jesse Grant/Getty Images

    Tori Spellingsaid she struggled to lose weight after the birth of her son Beau in 2017, and that she turned to a weight loss injection for help—but to no avail and that she's no longer on it. "I did Mounjaro and everyone admits it now. It’s a different time so I don’t feel shamed saying that," she said. "I did whatever anyone told me to do that was safe and it just wasn’t working. The weight wouldn’t come off."

    Caroline Stanbury

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    The Traitorsstar Caroline Stanburyrevealed on her podcast that she used Ozempic for weight loss and cited a particularly toxic and harmful quote from supermodel Kate Mossin her endorsement of the drug.

    "I used Ozempic, which I think is one of the best tools if you’re able to use it. What did Kate Moss say? ‘Nothing tastes as good as skinny feels,’" Stanbury said. "There’s something to be said for that."

    Related: Does Ozempic Make You Tired? Doctors Discuss Fatigue

    Patti Stanger

    Patti Stanger in January 2024

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    Millionaire MatchmakerPatti Stangerfirst used Ozempic, then stopped three weeks later after it gave her "the worst acid reflux."

    She still uses other weight loss drugs, however, today.

    "I waited, and all my hairdresser friends went on Mounjaro," she said on the Behind the Velvet Rope podcast. "I'm not diabetic, but I do take a sugar pill twice a day to keep my sugar down. So my doctor recommended it, and she said, 'I'll give you the vial of Tirzepatide,' which is the ingredient [in Mounjaro]."

    Eric Stonestreet

    Eric Stonestreet in July 2025

    Photo by Cindy Ord on Getty Images

    Modern Family star Eric Stonestreet takes Mounjaro for Type 2 diabetes and has been on the medication since it was first released in May 2022.

    He told PEOPLE, “It’s a game changer. It has just been incredible. It’s changed my lifestyle, changed my approach to eating, changed my approach to exercise.”

    Chrissy Teigen

    Chrissy Teigen in February 2026

    Photo by Michael Buckner on Getty Images

    Chrissy Teigen said she started using Ozempic after her miscarriage in 2020.

    “My body was completely stuck,” she said on her Self-Conscious podcast. “I really let myself indulge when I was pregnant. So, when I had lost that baby at 20 weeks, I had probably gained an extra 40 pounds that I wasn’t comfortable with.”

    Meghan Trainor

    Meghan Trainor in August 2025

    Photo by Peacock on Getty Images

    Meghan Trainor has a bit less bass now.

    The "Been Like This" singer wrote on Instagram in March 2025, "No, I don't look like I did 10 years ago. I've been on a journey to be the healthiest, strongest version of myself for my kids and for me. I’ve worked with a dietician [sic], made huge lifestyle changes, started exercising with a trainer and yes, I used science and support (shoutout to Mounjaro!) to help me after my 2nd pregnancy. And I’m so glad I did because I feel great."

    Trainor also got a breast augmentation as part of her makeover.

    Sheryl Underwood

    Sheryl Underwood in February 2023

    Unique Nicole/Getty Images

    The Talkhost Sheryl Underwoodtold The Messenger in December 2023 that she lost 100 pounds with the help of Wegovy, which also helped her ease off medications she was on for other health issues.

    "I'm about three different sizes because I still got a booty," she said, joking that she's a "baby Kardashian."

    Related: What Happens if You Eat Too Much Sugar on Ozempic, According to Obesity Doctors

    Serena Williams

    Serena Williams in November 2025

    Photo by Michael Buckner on Getty Images

    Serena Williams turned to weight loss drugs after welcoming her second child and struggling to lose her baby weight. Williams lamented that she dieted, "walked for hours" and hit the gym to no avail, ultimately using a GLP-1 and becoming a spokesperson for Ro.

    She explained to TODAY, “A misconception is that [weight loss medication] is a shortcut. As an athlete and as someone that has done everything, I just couldn’t get my weight to where I needed to be at a healthy place—and believe me, I don’t take shortcuts.”

    Vanessa Williams

    Vanessa Williams in February 2026

    Photo by Bruce Glikas on Getty Images

    Vanessa Williams called weight loss drugs a "game changer" for her body during and after menopause.

    "When I turned 60, I was like: ‘I want to be here for a long time, and I want to look my best. So what am I going to do?’" the singer, actress and former model told Hello! Magazine. "My fifties were hard. I started perimenopause in my late forties but suddenly, at 51, it’s crazy how your body changes. You feel out of control because you’re working out the same way, eating the same, and your body is not reacting the way it used to."

    Related: Ozempic Shortage? What to Do, According to Doctors

    Rebel Wilson

    Rebel Wilson in July 2024

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    After embarking on what she called a "year of health" to focus on diet and exercise as part of her fertility journey, Rebel Wilsonfinally admitted in March 2024 that she used a weight loss drug previously. She didn't specify what drug she used, but told The Sunday Times, "Someone like me could have a bottomless appetite for sweets, so I think those drugs can be good."

    Related: Ozempic Breasts: Doctors Explain What It Is and How to Treat It

    Oprah Winfrey

    Oprah Winfrey in January 2024

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    Billionaire Oprah Winfreyopened up about using weight loss drugs in December 2023. Winfrey, who owns a majority stake in WW (formerly Weight Watchers), revealed her decision to use unspecified weight loss medications after WW launched their own initiatives with the drugs.

    "The fact that there's a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for," she told PEOPLE. "I'm absolutely done with the shaming from other people and particularly myself."

    Winfrey incorporates the drugs on what she says was an as-needed basis in conjunction with diet and lifestyle changes. It's important to note that Winfrey's self-described occasional use of medications like Ozempic, Mounjaro and Wegovy goes against doctor recommendations, which are to use medications long-term.

    Related: A Large New Study on Weight Loss Drugs Like Wegovy Has Good News if You’re Looking To Reduce Your Heart Attack Risk

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