It can be challenging to keep all your nutrient bases covered, especially when your days and weeks are booked and busy. While all nutrients and micronutrients are important, some get talked about more than others. For example, you’re probably aware of the reasons why protein, fiber and vitamin D are important, and you might prioritize them in your diet. But what about vitamins A and E? Both of these are crucial, but they typically aren’t talked about nearly as much.Vitamin A is an important nutrient for eye health. Besides vision, it also supports immune function. Vitamin E is an antioxidant that protects cells, which is key to disease prevention. While it’s best to meet your nutrient needs through diet, supplements can help fill in the gap when this doesn’t happen. Vitamin A and E are both fat-soluble vitamins. Does this mean you can take vitamin A and E supplements together? After all, there are some combinations doctors urge patients to avoid, and other warnings about supplement safety to keep in mind. Before you integrate them into your wellness routine, here’s what you need to know—including who can benefit the most from taking a vitamin A or E supplement.Related: Want To Improve Your Brain Health? Experts Agree This Is the Most Important Supplement To Take
Dr. Heather Hughes, PharmD, a pharmacist and the group vice president of health, wellness and nutrition at Walgreens, tells Parade that conditions like cystic fibrosis and Crohn’s disease can make it harder for the body to absorb fat-soluble vitamins like vitamin A and E, so individuals with these health conditions may want to consider taking vitamin A and E supplements.
Vitamin A is found in a wide range of foods, including sweet potatoes, spinach, pumpkin, carrots, eggs and dairy products. It’s recommended to get between 700 and 900 micrograms of vitamin A a day, depending on your age and gender.
While severe vitamin A deficiency is rare in the U.S., Dr. Yoshua Quinones, MD, an internist with Medical Offices of Manhattan and a contributor to Lab Finder, says that there are certain people who can benefit from taking a vitamin A supplement. “People who can benefit from vitamin A supplements are those who are immunocompromised, malnourished, have intestinal malabsorption issues or severe liver disease,” he explains.
“Beyond addressing deficiency, vitamin A can be used to support eye health and bone growth, and it helps maintain healthy urinary, respiratory and intestinal tracts, which is important for overall health and immunity,” Dr. Hughes adds about its benefits.
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Vitamin E
What about vitamin E? This nutrient is found in sunflower seeds (and sunflower oil), almonds, hazelnuts, peanuts, spinach, broccoli, kiwi and more. It’s recommended to get 15 milligrams of vitamin E a day. Unless you are immunocompromised, malnourished or have one of the health conditions that Dr. Hughes mentioned above, you likely don’t need to take a vitamin E supplement.
“Several studies have shown harmful effects of vitamin E supplementation,” says Dr. David Cutler, MD, a family medicine physician at Providence Saint John’s Health Center in Santa Monica, California. Dr. Cutler explains that there is a bleeding risk when vitamin E is combined with certain blood-thinning medications and adds that high-dose vitamin E supplements are associated with an increased risk of hemorrhagic strokes.
If you have cancer, Dr. Cutler says you should also avoid taking a vitamin E supplement. “Studies of cancer patients have demonstrated worse outcomes for those taking vitamin E supplements. And one study found that 400 units of vitamin E daily increased the risk of prostate cancer,” he explains.
“The safest, most effective way to assure adequate vitamin E is through a balanced, healthy diet which includes nuts, seeds, vegetable oils, leafy green vegetables and avocado. Supplements of vitamin E should not be taken routinely, but only if there is a documented deficiency, a known medical indication or where dietary intake cannot be assured. While many typical American diets do not contain the recommended daily allowance of vitamin E, the preferred way to correct this is with a better diet, rather than supplements,” Dr. Cutler says.
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Is It Safe To Take Vitamin A and E Together?
If you are taking vitamin A and vitamin E supplements, it’s important to know how to safely integrate them into your routine. Dr. Hughes recommends talking to a doctor or pharmacist before starting any new vitamin, and warns against taking vitamin A and E in high doses.
“Both vitamins A and E are fat-soluble, which means they are stored in your liver and body fat rather than being flushed out easily. This can lead to a buildup in your body over time, potentially causing vitamin toxicity,” Dr. Hughes explains. To avoid getting too much of either vitamin, she recommends sticking with the previously mentioned daily recommendations.
Related: Doctors Say You Should Avoid These 4 Popular Supplements—and Take These Instead
As long as the doses of vitamin A and E in the supplements you’re taking fall within the recommended guidelines, Dr. Hughes and Dr. Quinones both say they can be taken together. Since they’re fat-soluble vitamins (which means they dissolve in fat), Dr. Quinones recommends taking them with food, specifically fat-containing foods such as avocado, seeds, nuts or fish. If you are taking high-dose vitamin A and E supplements, Dr. Quinones recommends taking them two to four hours apart.
Remember, ideally you should meet your nutrient needs through diet, and both vitamin A and E are found in a wide range of foods that fit into any dietary style. But if blood tests show that you aren’t getting enough or you have a health condition that is preventing your body from absorbing them through the foods you eat, talk to your doctor before integrating supplements into your routine. That way, you can make sure you’re taking them safely and you're getting your money’s worth.
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Sources:
Dr. Yoshua Quinones, MD, internist with Medical Offices of Manhattan and a contributor to Lab FinderDr. Heather Hughes, PharmD, pharmacist and the group vice president of Health, Wellness & Nutrition at WalgreensDr. David Cutler, MD, family medicine physician at Providence Saint John’s Health Center in Santa Monica, CaliforniaVitamin A. StatPearlsVitamin E. StatPearls Vitamin A and Carotenoids. National Institutes of Health. Office of Dietary SupplementsVitamin E. National Institutes of Health. Office of Dietary SupplementsKaye, A. D., Thomassen, A. S., Mashaw, S. A., et al. (2025). Vitamin E (a-Tocopherol): Emerging Clinical Role and Adverse Risks of Supplementation in Adults. Cureus. 17(2):e78679. Jabbari, P., Yazdanpanah, O., Benjamin, D., et al. (2024). Supplement Use and Increased Risks of Cancer: Unveiling the Other Side of the Coin.Cancers. 16(5):880Hence then, the article about is it safe to take vitamin a and e supplements together was published today ( ) and is available on Parade ( Saudi Arabia ) The editorial team at PressBee has edited and verified it, and it may have been modified, fully republished, or quoted. You can read and follow the updates of this news or article from its original source.
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