Fantasy Football Defense Rankings Week 10: Best Starts at D/ST ...Middle East

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Fantasy Football Defense Rankings Week 10: Best Starts at D/ST

Fantasy Football Expert Justin Edwards looks at the current Fantasy Football Defense rankings and projections for Week 10.

“After nine weeks of NFL action, there are a number of surprises in the football landscape, and the fantasy football Defense rankings are reflecting that.”

    2025 Fantasy Football Defense Rankings

    *As always, the projections and rankings are courtesy of 4for4’s Fantasy Football Defense rankings! 

    #TeamFF Pts1Broncos7.42Panthers7.23Jets6.94Seahawks6.75Lions6.76Bills6.57Rams6.48Ravens6.49Browns6.310Texans6.311Packers6.212Bears6.213Buccaneers6.214Colts6.215Jaguars616Patriots5.617Chargers5.518Steelers5.519Vikings5.42049ers5.4 Robert Deutsch / USA TODAY NETWORK via Imagn Images

    Fantasy Football D/ST Rankings, Who Should I Add Off Waiver Wires:

    The Seattle Seahawks were the highest recommended D/ST waiver wire pickups this week.

    Analysis

    Seahawks — Rostered in 58% of Yahoo Leagues

    The only reason the Seahawks are this available is because they were on bye in Week 8 and then faced Jayden Daniels’ Commanders in Week 9. They’ve been one of the best defenses in the NFL (and in fantasy) and are probably worth playing every week down the stretch (except maybe Week 15 against the Colts). Consider them a high-priority add.

    Read Matt Okada’s full Week 10 Waiver Wire Watch

    What is another Matchup to Exploit in the Fantasy Football Defense Rankings?

    The Carolina Panthers and Cleveland Browns stick out with a positive matchup during Week 10.

    Analysis

    Panthers vs. Saints

    Heading into the week, the New Orleans Saints are dead last in blown block rate (3.85%). That was before shipping starting left guard Trevor Penning out to L.A. to presumably try to replace Joe Alt, who hit the season-ending IR from an ankle injury suffered over the weekend. The fallout from the Saints’ side of the deal should equate to Dillon Radunz sliding back into the starting lineup after filling in for Penning through the first two weeks of the season.

    The former second-round pick of the Tennessee Titans (2021) has performed as a below-replacement-level guard through his five-year career, boasting a 96.3 pass-block efficiency rate that would rank 50th out of 59 qualifying guards if applied to this season alone.

    The other big trade that sent WR Rashid Shaheed to Seattle also lowers the ceiling on what was already a limited offense, making the Saints an even bigger target for opposing D/STs for the rest of the season. The Panthers are an easy D/ST selection for any managers who need a streaming play, and should be a chalky selection in Sunday DFS lineups.

    Browns @ Jets

    The New York Jets’ offensive line has shown flashes of improvement throughout the season, but it’s still been a wildly inconsistent group, allowing an incredible 49.2% QB pressure rate —by far the highest in the league. As such, Justin Fields has taken a sack on every 9.59 dropbacks, the second-highest rate in the league. We still don’t know who will be taking the snaps in this game —or for how long— but that shouldn’t matter much, as Tyrod Taylor sits directly behind Fields with a sack every 10.1 dropbacks, the third-highest rate.

    This has led to the Jets ranking 28th in schedule-adjusted fantasy points allowed to opposing defenses, and with Myles Garrett coming into town, things figure to be worse before they get better. The Browns have 3+ sacks in six games this season, and with the New York sending away their two best defensive players at the trade deadline, Cleveland is the betting favorite in this game despite their own offensive troubles. Expect a nearly unwatchable, gritty, 1960s-style slog, with the Browns as an easy D/ST floor play.

    *Read Justin Edwards’ full O-Line Rankings and Matchups to Exploit: Week 10*

    Who are some Week 10 Fantasy Defenses to avoid?

    Some options that have fallen out of the top-20 Fantasy Football Defense Rankings include: the Philadelphia Eagles, New Orleans Saints, and Miami Dolphins.

    For more advice on who to start, check out the Fantasy Football DST Rankings Week 10

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