Chicago Cubs Lineup: Taking on a Lefty ...Middle East

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Chicago Cubs Lineup: Taking on a Lefty

CUBS LINEUP — The Cubs were nearly no-hit last night by Hunter Greene, which we’ll chalk up to post-clinch revelry. Here’s hoping tonight is a little more back-to-normal.

Chicago Cubs Lineup:

Night two in Cincinnati.Watch live on the Marquee Sports Network App. pic.twitter.com/Ebd5zTZz7R

    — Chicago Cubs (@Cubs) September 19, 2025

    Facing a lefty tonight (albeit one with some reverse splits this year, discussed below), Craig Counsell loads up on righties, including getting both Justin Turner and Carlos Santana in there. Stay off the changeup, boys.

    Cincinnati Reds Lineup:

    One game at a time. Powered by @PNCBank pic.twitter.com/WWxnVivgB2

    — Cincinnati Reds (@Reds) September 19, 2025

    Pitching Matchup:

    Chicago Cubs: Shōta Imanaga, LHP

    Shōta Imanaga has not allowed more than three earned runs in a start since July 25. Then again, Imanaga has allowed exactly three earned runs in six of those nine starts, including the last four in a row. You’d like to see him break that streak in a positive direction, but it’s tough to be a fly ball lefty pitching at Great American Ballpark.

    Cincinnati Reds: Nick Lodolo, LHP

    Although the monster breakout has never quite happened, the 27-year-old lefty is putting together the best season of his career (3.30 ERA, 3.86 FIP over 144.2 innings). Lodolo has modest traditional splits for his career, but this season, he has DOMINATED righties while getting blown up by lefties. Guessing his monster changeup this year has a whole lot to do with that, so watch out, righties.

    Broadcast Info:

    Chicago Cubs (88-65) vs Cincinnati Reds (77-76) at 5:50 pm CT – Marquee, 670 The Score

    Cubs vs Reds – Key Injuries:

    Chicago Cubs:

    Owen Caissie, OF Miguel Amaya, C Kyle Tucker, OF Ryan Brasier, RP Daniel Palencia, RP Eli Morgan, RHP Justin Steele, LHP

    Cincinnati Reds:

    Brandon Williamson, SP Julian Aguiar, SP Rhett Lowder, SP Tyler Callihan, IF/OF Wade Miley, SP Ian Gibaut, RP Carson Spiers, SP

    Cubs vs Reds – Great American Ballpark Weather Report

    Location: Cincinnati, OHTemperature: 83 degreesWind: Blowing out to right, but barely at all (2-3 MPH)

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