The New York Yankees (85-67), led by Trent Grisham on a two-game home run streak, are -120 favorites on the moneyline to defeat Dylan Beavers (homers in two straight contests) and the Baltimore Orioles (72-80). First pitch is at 7:05 p.m. ET on Friday, live from Oriole Park at Camden Yards and airing on MASN and YES.
Will Warren will get the ball for New York while Baltimore will counter with Trevor Rogers.
Yankees vs. Orioles Odds
Yankees odds to win: -120 Orioles odds to win: +100 Spread: Yankees -1.5 Total: 9 runsYankees vs. Orioles Promo Codes
Game Time and Information
Date: Friday, September 19, 2025 Time: 7:05 p.m. ET TV: MASN and YESWho Will Win Yankees vs. Orioles?
Yankees and Orioles Betting Trends
The Yankees have won 58.1% of the games this season when they were the moneyline favorite (75-54).
New York has gone 71-51 (winning 58.2% of its games) when playing as moneyline favorites of -120 or shorter.
The Orioles have won 39, or 45.9%, of the 85 games they’ve played as underdogs this season.
Baltimore has entered 72 games this season as the underdog by +100 or more and is 33-39 in those contests.
The Yankees have played in 151 games with an over/under set, and have combined with their opponents to go over the total 74 times (74-71-6).
So far this season, the Orioles and their opponents have hit the over in 63 of their 152 games with a total.
Yankees Stats & Insights
The Yankees have the No. 1 offense in baseball scoring 5.2 runs per game (794 total runs).
The New York Yankees lead baseball with 258 total home runs, averaging 1.7 per game.
The Yankees’ .250 batting average ranks 12th in the majors.
New York’s batters strike out 8.9 times per game, the 28th-most in baseball.
The nine strikeouts per nine innings compiled by the Yankees pitching staff ranks fourth in the majors.
New York’s 4.06 team ERA ranks 18th among all MLB pitching staffs.
Orioles Stats & Insights
The Orioles have scored 650 runs (4.3 per game) this season, which ranks 23rd in MLB.
Baltimore’s 180 home runs rank 12th in Major League Baseball.
The Orioles have a team batting average of .239 this season, which ranks 23rd among MLB teams.
Baltimore ranks just 26th in MLB in strikeouts per game with an average of 8.9 whiffs per contest.
The Orioles have an 8.4 K/9 this season as a pitching staff, which ranks 17th in the big leagues.
Baltimore has pitched to a 4.60 ERA this season, which ranks 24th in baseball.
Yankees Key Players to Watch
Warren (8-7 with a 4.44 ERA and 160 strikeouts in 152 2/3 innings pitched) makes the start for the Yankees, his 32nd of the season.
Aaron Judge is batting .329 with 48 home runs and 103 RBI. All three of those stats rank first among New York hitters this season.
Cody Bellinger has 152 hits and an OBP of .331 to go with a slugging percentage of .495 this season.
Grisham has 111 hits this season and a slash line of .240/.348/.478.
Jazz Chisholm has 104 hits and an OBP of .332 to go with a slugging percentage of .477 this season.
Orioles Key Players to Watch
The Orioles will hand the ball to Rogers (8-2) for his 17th start of the season.
Gunnar Henderson leads the Orioles in runs batted in (64) and has accumulated a team-high batting average of .274.
Jackson Holliday has put his power on display as he paces his team with 17 home runs.
Jordan Westburg is batting .268 with nine doubles, a triple, 15 home runs and 17 walks.
Colton Cowser has 12 doubles, 15 home runs and 22 walks while batting .199.
Yankees and Orioles Injuries
Yankees: Jonathan Loaisiga: 15 Day IL (Back), Brent Headrick: 15 Day IL (Forearm), Gerrit Cole: 60 Day IL (Elbow), Oswaldo Cabrera: 60 Day IL (Ankle), Clarke Schmidt: 60 Day IL (Forearm), Jake Cousins: 60 Day IL (Elbow)
Orioles: Adley Rutschman: 10 Day IL (Oblique), Shawn Dubin: 15 Day IL (Elbow), Colin Selby: 15 Day IL (Hamstring), Albert Suarez: 15 Day IL (Elbow), Felix Bautista: 60 Day IL (Shoulder), Scott Blewett: 60 Day IL (Elbow), Zach Eflin: 60 Day IL (Back), Grayson Rodriguez: 60 Day IL (Elbow), Brandon Young: 60 Day IL (Hamstring), Gary Sánchez: 60 Day IL (Knee), Trevor Rogers: day-to-day (Toe)
Yankees vs. Orioles Prediction
Score Prediction: Yankees 5, Orioles 4 Total Prediction: Under 9 runsHow to Bet on Yankees vs. Orioles
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