Yankees vs. Twins Prediction: Expert Picks, Odds, Stats & Best Bets – Tuesday, September 16, 2025 ...Middle East

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Yankees vs. Twins Prediction: Expert Picks, Odds, Stats & Best Bets – Tuesday, September 16, 2025

The New York Yankees will take the field against the Minnesota Twins (65-84) on Tuesday. The game begins at 7:40 p.m. ET on MNNT and YES, with the Yankees listed as -167 favorites on the moneyline.

Cam Schlittler starts for New York while Zebby Matthews is Minnesota’s starter for the contest.

    Yankees vs. Twins Odds

    Yankees odds to win: -167 Twins odds to win: +140 Spread: Yankees -1.5 Total: 9 runs

    Yankees vs. Twins Promo Codes

    Game Time and Information

    Date: Tuesday, September 16, 2025 Time: 7:40 p.m. ET TV: MNNT and YES

    Who Will Win Yankees vs. Twins?

    Yankees and Twins Betting Trends

    The Yankees have won 73 of the 126 games they were favored on the moneyline this season (57.9%).

    New York has a 37-18 record (winning 67.3% of its games) when playing as moneyline favorites of -167 or shorter.

    The Twins have entered the game as underdogs 59 times this season and won 23, or 39%, of those games.

    Minnesota has entered 14 games this season as the underdog by +140 or more and is 5-9 in those contests.

    The Yankees have combined with opponents to hit the over on the total 72 times this season for a 72-70-6 record against the over/under.

    The Twins and their opponents have gone over the total this season in 70 of their 148 opportunities.

    Yankees Stats & Insights

    The Yankees have the most productive offense in baseball scoring 5.2 runs per game (774 total runs).

    The New York Yankees average 1.7 home runs per game and have hit an MLB-best 254 home runs in total.

    The Yankees’ .249 batting average ranks 12th in MLB.

    New York’s hitters strike out 8.9 times per game, the 28th-most in baseball.

    The nine strikeouts per nine innings put together by the Yankees pitching staff ranks fourth in the majors.

    New York’s 4.00 team ERA ranks 16th among all MLB pitching staffs.

    Twins Stats & Insights

    The Twins have scored 632 runs (4.2 per game) this season, which ranks 25th in MLB.

    Minnesota has hit 178 homers this season, which ranks 11th in the majors.

    The Twins have a team batting average of .239 this season, which ranks 22nd among MLB teams.

    Minnesota ranks 15th with an average of 8.3 strikeouts per game.

    The Twins have an 8.6 K/9 this season as a pitching staff, which ranks 12th in the big leagues.

    Minnesota pitchers have a combined ERA of 4.62 ERA this year, which ranks 24th in MLB.

    Yankees Key Players to Watch

    Schlittler (3-3) takes the mound for the Yankees in his 12th start of the season. He has a 3.05 ERA in 56 2/3 innings pitched, with 63 strikeouts.

    Aaron Judge is batting .326 with 48 home runs and 102 RBI. All three of those stats rank first among New York hitters this season.

    Cody Bellinger has collected 149 hits this season and has an OBP of .332. He’s slugging .496 on the year.

    Jazz Chisholm has collected 102 base hits, an OBP of .337 and a slugging percentage of .488 this season.

    Trent Grisham has 107 hits and an OBP of .346 to go with a slugging percentage of .461 this season.

    Twins Key Players to Watch

    The Twins’ Matthews (4-5) will make his 15th start of the season.

    Byron Buxton leads the Twins in home runs (31), runs batted in (76) and has accumulated a team-high batting average of .270.

    Trevor Larnach is hitting .252 with 21 doubles, a triple, 16 home runs and 50 walks.

    Brooks Lee is batting .235 with 14 doubles, a triple, 14 home runs and 30 walks.

    Kody Clemens has 11 doubles, three triples, 19 home runs and 26 walks while hitting .216.

    Yankees and Twins Injuries

    Yankees: Jonathan Loaisiga: 15 Day IL (Back), Brent Headrick: 15 Day IL (Forearm), Gerrit Cole: 60 Day IL (Elbow), Oswaldo Cabrera: 60 Day IL (Ankle), Clarke Schmidt: 60 Day IL (Forearm), Jake Cousins: 60 Day IL (Elbow), Anthony Volpe: day-to-day (Shoulder)

    Twins: Christian Vázquez: 10 Day IL (Shoulder), Anthony Misiewicz: 15 Day IL (Shoulder), David Festa: 15 Day IL (Shoulder), Justin Topa: 15 Day IL (Oblique), Alan Roden: 60 Day IL (Thumb), Ryan Jeffers: 7 Day IL (Head)

    Yankees vs. Twins Prediction

    Score Prediction: Yankees 6, Twins 5 Total Prediction: Over 9 runs

    How to Bet on Yankees vs. Twins

    Get more MLB picks. If you are new to sports betting, read our in-depth guide on betting on Baseball and find the best MLB betting sites and promo codes.

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