Nationals vs. Pirates Prediction: Expert Picks, Odds, Stats & Best Bets – Friday, September 12, 2025 ...Middle East

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Nationals vs. Pirates Prediction: Expert Picks, Odds, Stats & Best Bets – Friday, September 12, 2025

The Washington Nationals (60-86) are favored on the moneyline (-110) in Friday’s contest against the Pittsburgh Pirates (64-83). Game time is at 6:45 p.m. ET on MASN and SportsNet PT. The Pirates, with +156 odds, are favored against the spread (1.5).

Brad Lord will get the ball for Washington while Pittsburgh will counter with Mitch Keller.

    Nationals vs. Pirates Odds

    Nationals odds to win: -110 Pirates odds to win: -109 Spread: Pirates -1.5 Total: 8 runs

    Nationals vs. Pirates Promo Codes

    Game Time and Information

    Date: Friday, September 12, 2025 Time: 6:45 p.m. ET TV: MASN and SportsNet PT

    Who Will Win Nationals vs. Pirates?

    Nationals and Pirates Betting Trends

    The Nationals have put together a 6-12 record in games they were listed as the moneyline favorite (winning 33.3% of those games).

    Washington has a record of 6-12 when it has played as moneyline favorites with odds of -110 or shorter (33.3% winning percentage).

    The Pirates have been underdogs in 104 games this season and won 43 (41.3%) of those contests.

    Pittsburgh is 42-60 this season when entering a game as the underdog by -109 or more on the moneyline.

    The Nationals have had an over/under set by oddsmakers 145 times, and have combined with opponents to go over the total in 73 of those games (73-64-8).

    So far this season, the Pirates and their opponents have hit the over in 60 of their 146 games with a total.

    Nationals Stats & Insights

    The Nationals have the No. 22 offense in baseball scoring 4.3 runs per game (626 total runs).

    Washington ranks 25th in MLB with 140 total home runs.

    The Nationals’ .245 batting average ranks 17th in MLB.

    Washington strikes out 8.1 times per game to rank eighth in baseball.

    The Nationals pitching staff ranks 27th in the majors with a collective 7.8 strikeouts per nine innings.

    Washington’s 5.30 team ERA ranks 29th among all MLB pitching staffs.

    Pirates Stats & Insights

    The Pirates have scored 527 runs (just 3.6 per game) this season, which ranks last in MLB.

    Pittsburgh has hit just 105 homers this season, which ranks last in the majors.

    The Pirates have a team batting average of just .232 this season, which ranks 28th among MLB teams.

    Pittsburgh ranks 23rd in MLB in strikeouts per game with an average of 8.8 Ks per contest.

    The Pirates strike out 8.1 batters per nine innings as a pitching staff, 21st in MLB.

    Pittsburgh has the 11th-ranked ERA (3.88) in the majors this season.

    Nationals Key Players to Watch

    Lord (5-8) gets the starting nod for the Nationals in his 16th start of the season. He has a 4.20 ERA in 109 1/3 innings pitched, with 92 strikeouts.

    C.J. Abrams leads Washington in batting average (.266) this season while adding 17 home runs and 53 RBI.

    James Wood is batting .260 this season with a team-high 27 home runs and 88 RBI.

    Luis Garcia has 117 hits this season and a slash line of .262/.300/.415.

    Josh Bell is batting .234 with an OBP of .324 and a slugging percentage of .409 this season.

    Pirates Key Players to Watch

    Keller (6-14) will take the mound for the Pirates, his 30th start of the season.

    Bryan Reynolds paces the Pirates with 70 runs batted in.

    Andrew McCutchen has a club-high .244 batting average.

    Oneil Cruz has hit a team-best 19 homers.

    Tommy Pham is hitting .256 with 17 doubles, a triple, nine home runs and 42 walks.

    Nationals and Pirates Injuries

    Nationals: Drew Millas: 60 Day IL (Finger), Josiah Gray: 60 Day IL (Elbow), Trevor Williams: 60 Day IL (Elbow), DJ Herz: 60 Day IL (Elbow), Derek Law: 60 Day IL (Forearm), Keibert Ruiz: 7 Day IL (Concussion)

    Pirates: Jack Suwinski: 10 Day IL (Groin), Ronny Simon: 10 Day IL (Shoulder), Justin Lawrence: 60 Day IL (Elbow), Endy Rodriguez: 60 Day IL (Elbow), Jared Jones: 60 Day IL (Elbow), Enmanuel Valdez: 60 Day IL (Shoulder)

    Nationals vs. Pirates Prediction

    Score Prediction: Nationals 6, Pirates 5 Total Prediction: Over 8 runs

    How to Bet on Nationals vs. Pirates

    Get more MLB picks. If you are new to sports betting, read our in-depth guide on betting on Baseball and find the best MLB betting sites and promo codes.

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