The San Francisco Giants (72-69) are +130 underdogs for their meeting with the St. Louis Cardinals (70-72) on Sunday at 2:15 p.m. ET. Rafael Devers has 99 RBI on the season and will hope to hit his milestone 100th once the game begins at Busch Stadium, live on FDSMW and NBCS-BA.
Sonny Gray gets the starting nod for St. Louis while Kai-Wei Teng is San Francisco’s starter for the contest.
Cardinals vs. Giants Odds
Cardinals odds to win: -155 Giants odds to win: +130 Spread: Cardinals -1.5 Total: 7.5 runsCardinals vs. Giants Promo Codes
Game Time and Information
Date: Sunday, September 7, 2025 Time: 2:15 p.m. ET TV: FDSMW and NBCS-BAWho Will Win Cardinals vs. Giants?
Cardinals and Giants Betting Trends
The Cardinals have a 33-32 record in games they were listed as the moneyline favorite (winning 50.8% of those games).
St. Louis has a record of 9-8 when it has played as moneyline favorites with odds of -155 or shorter (52.9% winning percentage).
This season, the Giants have been the underdog 58 times and won 28, or 48.3%, of those games.
San Francisco has a record of 5-11 in games where sportsbooks have it as underdogs of at least +130 on the moneyline.
The Cardinals have had an over/under set by oddsmakers 141 times, and have combined with opponents to go over the total in 72 of those games (72-62-7).
The Giants and their opponents have gone over the total this season in 66 of their 141 opportunities.
Cardinals Stats & Insights
The Cardinals have the No. 16 offense in MLB play scoring 4.3 runs per game (615 total runs).
St. Louis has hit 136 home runs this season, the fifth-lowest total in MLB play.
The Cardinals’ .246 batting average ranks 17th in the majors.
St. Louis strikes out 7.9 times per game to rank ninth in MLB.
The 7.5 strikeouts per nine innings compiled by the Cardinals pitching staff ranks 29th in MLB.
St. Louis has a 4.30 team ERA that ranks 21st across all MLB pitching staffs.
Giants Stats & Insights
The Giants rank 18th in the majors with 613 total runs scored this season.
San Francisco ranks 19th in Major League Baseball with 152 home runs.
The Giants rank 24th in MLB with a .239 team batting average.
San Francisco ranks 19th with an average of 8.5 strikeouts per game.
The Giants strike out 8.6 batters per nine innings as a pitching staff, 11th in MLB.
San Francisco has pitched to a 3.77 ERA this season, which ranks fifth in baseball.
Cardinals Key Players to Watch
Gray gets the start for the Cardinals, his 29th of the season. He is 12-8 with a 4.43 ERA and 173 strikeouts through 158 1/3 innings pitched.
Masyn Winn has been key for St. Louis with nine home runs, 51 RBI and a batting average of .253 this season.
Lars Nootbaar is batting .240 with an OBP of .329 and a slugging percentage of .383 this season.
Ivan Herrera has collected 89 base hits, an OBP of .366 and a slugging percentage of .452 this season.
Victor Scott II has collected 80 hits this season and has an OBP of .314. He’s slugging .312 on the year.
Giants Key Players to Watch
The Giants will send Teng (2-3) to the mound for his fifth start this season.
Devers leads the Giants in home runs (31) and runs batted in (99).
Jung Hoo Lee is batting .267 with 30 doubles, 11 triples, seven home runs and 44 walks.
Willy Adames has 18 doubles, two triples, 27 home runs and 66 walks while batting .230.
Heliot Ramos has a club-high .269 batting average.
Cardinals and Giants Injuries
Cardinals: Alec Burleson: 10 Day IL (Wrist), Nolan Arenado: 10 Day IL (Shoulder), Brendan Donovan: 10 Day IL (Groin), John King: 15 Day IL (Back), Zack Thompson: 60 Day IL (Lat)
Giants: Jerar Encarnación: 10 Day IL (Hamstring), Landen Roupp: 15 Day IL (Knee), Carson Whisenhunt: 15 Day IL (Back), Tom Murphy: 60 Day IL (Back), Randy Rodriguez: 60 Day IL (Elbow), Erik Miller: 60 Day IL (Elbow)
Cardinals vs. Giants Prediction
Score Prediction: Cardinals 5, Giants 4 Total Prediction: Over 7.5 runsHow to Bet on Cardinals vs. Giants
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