Aaron Judge, batting .324 this season, leads the New York Yankees (76-61) into a matchup with Jeremy Pena (.307 AVG) and the Houston Astros (76-62). The Yankees are -125 favorites on the moneyline for the matchup at Daikin Park, beginning at 8:10 p.m. ET live on MLB Network, SCHN, and Amazon Prime Video.
New York’s Will Warren and Houston’s Jason Alexander have been named the starters for this contest.
Yankees vs. Astros Odds
Yankees odds to win: -125 Astros odds to win: +105 Spread: Yankees -1.5 Total: 9 runsYankees vs. Astros Promo Codes
Game Time and Information
Date: Wednesday, September 3, 2025 Time: 8:10 p.m. ET TV: MLB Network, SCHN, and Amazon Prime VideoWho Will Win Yankees vs. Astros?
Yankees and Astros Betting Trends
The Yankees have gone 66-49 in games they were favored on the moneyline (winning 57.4% of those games).
New York has a record of 63-43 when playing as moneyline favorites with odds of -125 or shorter (59.4% winning percentage).
The Astros have been underdogs in 44 games this season and won 26 (59.1%) of those contests.
Houston has a record of 17-13 in games where sportsbooks have it as underdogs of at least +105 on the moneyline.
The Yankees have combined with opponents to go over the total 66 times this season for a 66-65-5 record against the over/under.
Games involving the Astros have gone over the total set by oddsmakers in 62 of 138 chances this season.
Yankees Stats & Insights
The Yankees score the most runs in baseball (719 total, 5.2 per game).
The New York Yankees have hit an MLB-leading 233 home runs, averaging 1.7 per game.
The Yankees have the 10th-best batting average in the majors (.250).
New York strikes out 8.8 times per game, the No. 25 average in MLB.
The 9.1 strikeouts per nine innings put together by the Yankees pitching staff ranks third in the majors.
New York has a 3.92 team ERA that ranks 15th across all MLB pitching staffs.
Astros Stats & Insights
The Astros rank 23rd in the majors with 580 total runs scored this season.
Houston’s 153 home runs rank 18th in Major League Baseball.
The Astros rank fifth in MLB with a .253 team batting average.
Houston has shown good bat-to-ball skills at the plate this season with the seventh-best strikeout rate (7.9 per game) among MLB offenses.
The Astros average 9.6 strikeouts per nine innings as a pitching staff, first-most in the majors.
Houston pitchers have a combined ERA of 3.83 ERA this year, seventh-best in baseball.
Yankees Key Players to Watch
The Yankees will send Warren (8-6) out to make his 29th start of the season. He is 8-6 with a 4.30 ERA and 149 strikeouts through 136 2/3 innings pitched.
Judge leads New York in home runs with 43, runs batted in with 97 and his batting average of .324 is also best on his team.
Cody Bellinger has 138 hits and an OBP of .333 to go with a slugging percentage of .504 this season.
Trent Grisham has collected 101 base hits, an OBP of .356 and a slugging percentage of .477 this season.
Jazz Chisholm has 89 hits and an OBP of .339 to go with a slugging percentage of .487 this season.
Astros Key Players to Watch
The Astros’ Alexander (4-1) will make his ninth start of the season.
Jose Altuve has launched a team-best 24 home runs.
Pena is hitting .307 to lead his team.
Christian Walker has collected a team-best 74 RBI.
Yainer Diaz has 18 doubles, a triple, 18 home runs and 19 walks while batting .253.
Yankees and Astros Injuries
Yankees: Austin Slater: 10 Day IL (Hamstring), Jonathan Loaisiga: 15 Day IL (Back), Brent Headrick: 15 Day IL (Forearm), Gerrit Cole: 60 Day IL (Elbow), Oswaldo Cabrera: 60 Day IL (Ankle), Clarke Schmidt: 60 Day IL (Forearm), Jake Cousins: 60 Day IL (Elbow)
Astros: Jake Meyers: 10 Day IL (Calf), Bennett Sousa: 15 Day IL (Elbow), Josh Hader: 15 Day IL (Shoulder), John Rooney: 15 Day IL (Concussion / nasal), Brandon Walter: 60 Day IL (Elbow), Ronel Blanco: 60 Day IL (Elbow), Zach Dezenzo: 60 Day IL (Hand), Brendan Rodgers: 60 Day IL (Oblique), Isaac Paredes: 60 Day IL (Hamstring), Hayden Wesneski: 60 Day IL (Elbow), Pedro Leon: 60 Day IL (Knee), Victor Caratini: 7 Day IL (Concussion)
Yankees vs. Astros Prediction
Score Prediction: Yankees 5, Astros 4 Total Prediction: Under 9 runsHow to Bet on Yankees vs. Astros
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