The Cleveland Guardians (64-61) and the Arizona Diamondbacks (61-66) face off at Chase Field on Wednesday at 3:40 p.m. ET.
The Diamondbacks will give the nod to Brandon Pfaadt (12-8) against the Guardians and Parker Messick.
Diamondbacks vs. Guardians Pitcher Matchup and Game Info
When: Wednesday, August 20, 2025 at 3:40 p.m. ET Where: Chase Field in Phoenix, Arizona How to watch on TV: ARID and CLEG Probable Pitchers: Pfaadt – ARI (12-8, 5.01 ERA) vs Messick – CLE (0-0, 0.00 ERA)Diamondbacks vs. Guardians Odds
Guardians to win: +100 Total: 8.5 runsDiamondbacks vs. Guardians Pitcher Performance
Pfaadt Messick 25 GS 0 12-8 W-L 0-0 5.01 ERA – 133 IP 0 30 BB 0 108 SO 0Diamondbacks Probable Starting Pitcher: Brandon Pfaadt
Pfaadt (12-8) gets the starting nod for the Diamondbacks in his 26th start of the season. He’s put together a 5.01 ERA in 133 2/3 innings pitched, with 108 strikeouts. The righty last appeared on Saturday against the Colorado Rockies, when he tossed six innings, allowing four earned runs while giving up eight hits. The 26-year-old has put up a 5.01 ERA and 7.3 strikeouts per nine innings across 25 games this season, while allowing a batting average of .279 to his opponents. Pfaadt has eight quality starts under his belt this season. Pfaadt will look to build on a four-game streak of going five or more innings (he’s averaging 5.3 frames per outing). He has held his opponents without an earned run in three of his 25 appearances this season.Diamondbacks vs. Guardians Promo Codes
Guardians Probable Starting Pitcher: Parker Messick
Messick will make his first start of the season for the Guardians. The left-hander will make his MLB debut at the age of 24.How to Bet on Diamondbacks vs. Guardians
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