The Boston Red Sox (65-54) serve as underdogs on the moneyline (+101) in Tuesday’s contest versus the Houston Astros (66-52). First pitch is at 8:10 p.m. ET on SCHN and NESN. The Red Sox are favored against the spread in this one (1.5) with +166 odds.
Spencer Arrighetti gets the starting nod for Houston while Dustin May is Boston’s starter for the contest.
Astros vs. Red Sox Odds
Astros odds to win: -121 Red Sox odds to win: +101 Spread: Red Sox -1.5 Total: 8.5 runsAstros vs. Red Sox Promo Codes
Game Time and Information
Date: Tuesday, August 12, 2025 Time: 8:10 p.m. ET TV: SCHN and NESNWho Will Win Astros vs. Red Sox?
Astros and Red Sox Betting Trends
The Astros have been favored on the moneyline 80 total times this season. They’ve gone 43-37 in those games.
Houston has a 30-27 record (winning 52.6% of its games) when playing as moneyline favorites of -121 or shorter.
This season, the Red Sox have been the underdog 45 times and won 21, or 46.7%, of those games.
Boston has a record of 17-18 in games where oddsmakers have it as underdogs of at least +101 on the moneyline.
The Astros have had an over/under set by bookmakers 118 times, and have combined with opponents to go over the total in 52 of those games (52-60-6).
The Red Sox and their opponents have gone over the total this season in 58 of their 118 opportunities.
Astros Stats & Insights
The Astros are the 16th-highest scoring team in MLB play averaging 4.3 runs per game (513 total).
Houston is 16th in baseball with 131 total home runs.
The Astros rank second in MLB with a .258 batting average.
Houston strikes out 7.8 times per game to rank seventh in MLB.
The Astros pitching staff is No. 1 in MLB with a collective 9.7 strikeouts per nine innings.
Houston’s 3.69 team ERA ranks seventh among all MLB pitching staffs.
Red Sox Stats & Insights
The Red Sox have scored the fourth-most runs in the league this season with 593.
Boston’s 143 home runs rank 11th in Major League Baseball.
The Red Sox’s .253 batting average is among the best in baseball, ranking eighth in MLB.
Boston ranks just 28th in MLB in strikeouts per game with an average of 8.9 whiffs per contest.
The Red Sox average the 18th-most strikeouts per nine innings (8.3) in the majors this season.
Boston pitchers have a combined ERA of 3.74 ERA this year, ninth-best in baseball.
Astros Key Players to Watch
The Astros are sending Arrighetti (1-2) out for his fourth start of the season. He is 1-2 with a 7.43 ERA and 13 strikeouts through 13 1/3 innings pitched.
Jose Altuve leads Houston in home runs (21) and runs batted in (63) this season while batting .287.
Jeremy Pena is batting .315 to lead Houston, while adding 12 homers and 44 runs batted in this season.
Yainer Diaz has collected 100 base hits, an OBP of .280 and a slugging percentage of .417 this season.
Carlos Correa has collected 105 hits this season and has an OBP of .335. He’s slugging .409 on the year.
Red Sox Key Players to Watch
May (6-8) will take to the mound for the Red Sox and make his 20th start of the season.
Jarren Duran leads the Red Sox with a .264 batting average.
Ceddanne Rafaela is batting .259 with 23 doubles, three triples, 14 home runs and 19 walks.
Trevor Story paces the Red Sox with 73 runs batted in.
Wilyer Abreu has shown off his power as he paces his team with 21 home runs.
Astros and Red Sox Injuries
Astros: Jake Meyers: 10 Day IL (Calf), Lance McCullers: 15 Day IL (Finger), Shawn Dubin: 15 Day IL (Forearm), Brandon Walter: 15 Day IL (Elbow), Ronel Blanco: 60 Day IL (Elbow), J.P. France: 60 Day IL (Shoulder), Zach Dezenzo: 60 Day IL (Hand), Brendan Rodgers: 60 Day IL (Oblique), Isaac Paredes: 60 Day IL (Hamstring), Hayden Wesneski: 60 Day IL (Elbow), Yordan Alvarez: 60 Day IL (Hand), Luis Garcia: 60 Day IL (Elbow), Pedro Leon: 60 Day IL (Knee)
Red Sox: Marcelo Mayer: 10 Day IL (Wrist), Triston Casas: 60 Day IL (Knee), Justin Slaten: 60 Day IL (Shoulder), Josh Winckowski: 60 Day IL (Elbow), Luis Guerrero: 60 Day IL (Elbow), Kutter Crawford: 60 Day IL (Knee), Patrick Sandoval: 60 Day IL (Elbow), Liam Hendriks: 60 Day IL (Hip), Tanner Houck: 60 Day IL (Flexor), Hunter Dobbins: 60 Day IL (Acl)
Astros vs. Red Sox Prediction
Score Prediction: Astros 5, Red Sox 4 Total Prediction: Over 8.5 runsHow to Bet on Astros vs. Red Sox
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