An NL Central matchup Saturday features the second-place Chicago Cubs (66-48) visiting the fourth-place St. Louis Cardinals (58-58). The Cubs (-170) are listed as favorites for the game, which gets underway at 7:15 p.m. ET from Busch Stadium.
Colin Rea will get the ball for Chicago while St. Louis will counter with Andre Pallante.
Cubs vs. Cardinals Odds
Cubs odds to win: -170 Cardinals odds to win: +143 Spread: Cubs -1.5 Total: 8.5 runsCubs vs. Cardinals Promo Codes
Game Time and Information
Date: Saturday, August 9, 2025 Time: 7:15 p.m. ET TV: FOXWho Will Win Cubs vs. Cardinals?
Cubs and Cardinals Betting Trends
The Cubs have won 53 of the 80 games they were listed as the moneyline favorite this season (66.2%).
Chicago has a record of 18-7 when playing as moneyline favorites with odds of -170 or shorter (72% winning percentage).
This season, the Cardinals have been the underdog 61 times and won 30, or 49.2%, of those games.
St. Louis has entered 13 games this season as the underdog by +143 or more and is 3-10 in those contests.
The Cubs have had an over/under set by bookmakers 114 times, and have combined with opponents to go over the total in 57 of those games (57-52-5).
The Cardinals’ games have gone over the total in 58 of their 115 chances.
Cubs Stats & Insights
The Cubs score the second-most runs in baseball (588 total, 5.2 per game).
Chicago is fourth-best in baseball with 164 total home runs.
The Cubs have the eighth-best batting average in the majors (.253).
Chicago’s hitters strike out 7.8 times per game, the fourth-lowest average in the majors.
The Cubs pitching staff ranks 28th in the majors with a collective 7.6 strikeouts per nine innings.
Chicago’s 3.90 team ERA ranks 15th across all MLB pitching staffs.
Cardinals Stats & Insights
The Cardinals rank 14th in the majors with 509 total runs scored this season.
St. Louis ranks 25th in Major League Baseball with 111 home runs.
The Cardinals rank 14th in MLB with a .249 team batting average.
St. Louis has shown good bat-to-ball skills at the plate this season with the eighth-best strikeout rate (7.8 per game) among MLB offenses.
The Cardinals have a 7.4 K/9 this season as a pitching staff, which ranks 29th in baseball.
St. Louis has the 20th-ranked ERA (4.22) in the majors this season.
Cubs Key Players to Watch
Rea makes the start for the Cubs, his 20th of the season. He is 8-5 with a 4.23 ERA and 79 strikeouts through 110 2/3 innings pitched.
Kyle Tucker has been key for Chicago with 111 hits, an OBP of .384 plus a slugging percentage of .474.
Pete Crow-Armstrong leads Chicago in home runs with 27 while driving in 78 runs and slugging .539.
Seiya Suzuki leads Chicago in home runs (27) and runs batted in (84) this season while batting .251.
Nico Hoerner leads Chicago in batting average (.292) this season while adding four home runs and 47 RBI.
Cardinals Key Players to Watch
Pallante (6-8) will take to the mound for the Cardinals and make his 23rd start of the season.
Brendan Donovan has put up a team-best batting average of .280.
Alec Burleson has 19 doubles, 14 home runs and 30 walks while hitting .279.
Willson Contreras has put up a team-best 16 home runs and 64 runs batted in.
Masyn Winn has 24 doubles, eight home runs and 29 walks while batting .270.
Cubs and Cardinals Injuries
Cubs: Jameson Taillon: 15 Day IL (Calf), Justin Steele: 60 Day IL (Elbow), Javier Assad: 60 Day IL (Oblique), Miguel Amaya: 60 Day IL (Oblique), Eli Morgan: 60 Day IL (Elbow), Mike Soroka: day-to-day (Shoulder)
Cardinals: Nolan Arenado: 10 Day IL (Shoulder), John King: 15 Day IL (Oblique), Zack Thompson: 60 Day IL (Lat)
Cubs vs. Cardinals Prediction
Score Prediction: Cubs 5, Cardinals 4 Total Prediction: Over 8.5 runsHow to Bet on Cubs vs. Cardinals
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