Nine dynamic duos to watch as 49ers enter mandatory minicamp ...Middle East

SANTA CLARA — Two practices remain in the 49ers’ offseason program, and they’ll come at mandatory minicamp today and Wednesday.

Only one practice each of the past two weeks was open to the media. This minicamp offers a greater chance to inspect this new-look crew.

While every player took part in at least some of the voluntary program, injuries figure to keep a handful of players shelved until at least training camp in six weeks, including wide receivers Ricky Pearsall (hamstring) and Brandon Aiyuk (knee), defensive tackle Alfred Collins (calf), and safeties Ji’Ayir Brown (ankle) and Malik Mustapha (knee).

Rather than single out those who’ve drawn praise, here are nine combinations to pique our curiosity:

1. Brock Purdy/Mac Jones

Purdy’s presence throughout the offseason program enhanced his command of the offense (and franchise), and it surely helped Jones see how things are supposed to be run as he takes over as Purdy’s understudy. All this went down while Purdy’s $265 million contract extension got hammered out behind the scenes. Jones had a poor practice last week, so minicamp offers a chance to rebound. Otherwise, we’ll be charting Tanner Mordecai’s snap count and stats closer in training camp.

2. Dee Winters/Nick Martin

Winters already had a shot at replacing Dre Greenlaw as All-Pro linebacker Fred Warner’s wingman a year ago, and while it didn’t go smoothly, Winters has looked better this spring. Martin arrives with speed and an upbeat vibe. Both are 5-foot-11, 220-plus pounds and eager to finally hit moving objects in camp and the preseason.

3. Spencer Burford/Austin Pleasants

Trent Williams and Colton McKivitz will be the offensive line’s starting bookends for a third straight season, but with Jaylon Moore gone to Kansas City, the 49ers need a new swing tackle. Burford is impressively transitioning from right guard to left tackle, while Pleasants has drawn praise from position coach Chris Foerster. Both could stick as backups. Andre Dillard signed to compete but didn’t take part in OTAs when the media was able to watch.

4. George Kittle/Luke Farrell

Farrell had 36 catches and none for touchdowns in four seasons in Jacksonville, so no one expects him to steal Kittle’s targets. But if the 49ers are to deploy more two-tight end formations, it’s been positive to have both involved this offseason. Meanwhile, the same backups are jockeying for roster spots, with Ross Dwelley back to contend with Jake Tonges, Brayden Willis, and Mason Pline.

5. Richie Grant/Jason Pinnock

Three months ago, the 49ers didn’t create much buzz with the addition of these veteran safeties, though their need eventually surfaced a month later when it became public that Mustapha is recovering from ACL reconstruction. With Brown (ankle surgery) also on the mend, the 49ers inserted Grant and Pinnock to learn defensive coordinator Robert Saleh’s scheme.

6. Nick Bosa/Mykel Williams

Six years after Bosa broke into the NFL as a first-round defensive end and eventual rookie of the year, he’s now mentoring Williams, this year’s No. 11 overall pick who seems highly receptive to any and all instruction, be it from Bosa or position coach Kris Kocurek. The Niners need that duo to, yes, sack the quarterback, but perhaps more importantly set the edge in a fortified run defense. Williams did not take part in team drills last Thursday.

7. Christian McCaffrey/Isaac Guerendo

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This is essentially a brand-new backfield tandem. After Guerendo rushed for 85 yards and his first touchdown last season against Dallas, McCaffrey made his season debut the next week at Tampa Bay and lasted three more games before exiting with a knee injury at Buffalo. Guerendo, who got one carry those first three games McCaffrey was back, eventually ended his rookie season getting carted off Arizona’s field with an MCL injury. Both look healthy now, and that is BIG for the offense.

8. Jauan Jennings/Demarcus Robinson

These veteran leaders are easily to overlook in the wide receiver corps, when most talk centers on Brandon Aiyuk’s knee recovery (and cryptical social-media posts), on Ricky Pearsall’s durability (hamstring, again), on Jordan Watkins (new kid in town) and on Jacob Cowing (second-year leap). Jennings didn’t practice last week, and Robinson is expected to be suspended because of last season’s arrest for alleged drunken driving, but both are comfortable and trustworthy targets for Purdy.

9. Upton Stout/Tre Brown

The 49ers invested a third-round pick on Stout to step in as a feisty nickel back. He’ll have to beat out Brown, who played the past four seasons with Seattle and intercepted Purdy two weeks ago. Also in the mix is Chase Lucas, who spent last season on the practice squad and has an off-field bond with Lenoir. Several other newcomers have shown promise — Tre Avery, Derrick Canteen, Dallis Flowers — and the 49ers need depth; potential starter Renardo Green exited Wednesday’s session with a knee issue of unknown severity.

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