New Alzheimer’s drug shows promise to prevent buildup of tau proteins in brain cells ...Middle East

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New Alzheimer’s drug shows promise to prevent buildup of tau proteins in brain cells
New Delhi, Oct 3 (IANS) In a promising breakthrough, an international team of researchers from the UK, US, and Japan has developed a new Alzheimer’s drug that effectively prevents the build-up of Tau proteins — a key driver of neurodegeneration. The drug, a peptide inhibitor called RI-AG03 blocked both Tau aggregation ‘hotspots’ for the first time in both lab and fruit fly studies. While Tau proteins play a crucial role in maintaining the structure and function of brain cells, these, however, malfunction in Alzheimer’s disease. The proteins clump together to form long and twisting fibrils, which when accumulated create neurofibrillary tangles. The masses of twisted Tau proteins then clog the

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