Researchers engineer mRNAs with multiple ‘tails’ to boost efficacy by 20x ...Middle East

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Researchers engineer mRNAs with multiple ‘tails’ to boost efficacy by 20x
New York, March 22 (IANS) Adding multiple “tails” to the new Messenger RNA (mRNA) structure can help improve its efficiency in cells by five to 20 times, according to a study. mRNA, which rose to fame with Covid-19 vaccines, are genetic sequences that instruct the body to produce proteins. Following its success against Covid, its prowess is also being explored to fight other diseases like cancer. But its broad use may depend on how long the mRNA molecules stay in the body, said the team from the Broad Institute of MIT and Harvard and MIT in the US. To find out, they engineered multi-tailed mRNAs, which were found to last two to three times longer in animals compared to unmodified mRNA. Furth

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