Indian scientists ace 1st human clinical trial of haemophilia A gene therapy ...Middle East

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Indian scientists ace 1st human clinical trial of haemophilia A gene therapy
New Delhi, Feb 28 (IANS) Scientists at the Christian Medical College (CMC) Vellore have successfully conducted the country’s first human clinical trial of gene therapy for haemophilia A (FVIII deficiency), Union Minister Dr. Jitendra Singh said on Wednesday. He said this while addressing the “National Science Day 2024” programme at Vigyan Bhawan here. Hemophilia A is a genetic disorder caused by missing or defective factor VIII (FVIII), a clotting protein, which means the patient bleeds longer than others. The clinical trials involved deploying a novel technology of using a lentiviral vector to express a FVIII transgene in the patient’s own haematopoietic stem cell, which will then express

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