US FDA examined 22 cases of cancers in CAR-T probe -officials ...Middle East

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US FDA examined 22 cases of cancers in CAR-T probe -officials
The U.S. Food and Drug Administration has been looking into 22 cases of T-cell cancers that occurred after treatment with CAR-T, two top FDA officials said on Wednesday, days after asking drugmakers to add a serious warning on the label of their cancer therapies that use the CAR-T technology. In an article published in the New England Journal of Medicine, the officials - Dr. Peter Marks and Dr. Nicole Verdun - said that secondary malignancies have been reported in conjunction with five of the six available CAR-T products and that the cancers included T-cell lymphoma, T-cell large granular lymphocytosis, peripheral T-cell lymphoma, and cutaneous T-cell lymphoma.

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