San Francisco 49ers general manager has revealed a huge update on the timeline return for Brandon Aiyuk.

49ers general manager John Lynch is reportedly working the phones, looking to update his team's roster by making a trade.

SANTA CLARA — DeMeco Ryans is in his third season as coach of the Houston Texans, something he never knew he wanted until Kyle Shanahan sat...

SANTA CLARA – The 49ers will encounter the NFL’s stingiest defense to score against Sunday in Houston.The Texans, conversely, will pit thei...

Turf toe is never as mild as the name implies.

SANTA CLARA – Trent Williams emerged from his rookie NFL season with a tip that altered his career and life.Move to Houston.That 2011 advi...

SANTA CLARA — The 49ers found some of their soul in their punch-in-the-mouth win over Atlanta.Now comes the hard part with the Houston Texa...

The 49ers’ ownership group added a new member Wednesday, as the team announced Pete Briger Jr. would be joining with a minority stake in the...

SANTA CLARA – Christian McCaffrey is the NFC’s offensive player of the week, a prize that George Kittle sought for his 49ers teammate prior...

SANTA CLARA — Before we pack up for back-to-back 49ers road trips to Houston and New Jersey’s Meadowlands, let’s unpack The Faithful’s socia...

The San Francisco 49ers were dealt another significant injury blow after Sunday's victory over the Atlanta Falcons.

Dre Greenlaw is appealing the suspension, according to multiple reports.

SANTA CLARA — Already challenged in terms of a pass rush, the 49ers got some bad news Monday when it was learned Bryce Huff came out of a 20...

Christian McCaffrey got some questionable help on his last touchdown.

SANTA CLARA — The game ended on fourth-and-10, with harried and hurried Atlanta quarterback Michael Penix Jr. throwing to no one in particul...