SANTA CLARA — Brandon Aiyuk has officially left the 49ers’ building — and roster, likely forever.Aiyuk’s stalled comeback from last season’...

The San Francisco 49ers have received some very concerning news regarding superstar running back Christian McCaffrey.

The San Francisco 49ers take on the Tennessee Titans on Sunday, Dec. 14 at 1:25 p.m. PDT at Levi’s Stadium.The Niners are coming off their...

SANTA CLARA – Their ugly-sweater Christmas party is done. The annual team picture is taken. A long-awaited bye in Week 14 has come and gone....

SANTA CLARA – Ricky Pearsall deployed a nifty double move to make arguably the 49ers’ biggest catch last game.His third-and-long conversion...

Coming off the bye week, the San Francisco 49ers find themselves in an enviable position. They are rested, getting healthier, and eyeing not...

Sometimes, budding rivalries are squelched by the schedule.The last two times the 49ers played the Philadelphia Eagles, there was no shorta...

SANTA CLARA – Best. In. The. World.Defensive end Clelin Ferrell used those four words in breaking down the 49ers’ huddle at Thursday’s prac...

SANTA CLARA — Christian McCaffrey is drawing a lot of attention as he zeroes in on becoming the first player in NFL history to have two seas...

Another tech executive joins Niners ownership.

A legendary Miami quarterback who backed up some of the greatest passers of his era over seven NFL seasons died.

The 49ers don't sound inclined to trade Mac Jones away in the offseason.

The Niners' schedule likely now includes the oldest player in the NFL.

SANTA CLARA – Keion White lined up on the New England Patriots’ defensive line two months ago and gleaned a strong first impression of the r...

SANTA CLARA — This 49ers season is so beguiling that they’ll improve their playoff stature without even playing in Week 14.Currently the NF...