The bottle was empty by the time the 49ers completed their upset.

49ers star TE George Kittle went down Sunday with a season-ending injury and had a unique request from the locker room.

The beloved 49ers defensive coordinator would not let Jalen Hurts into the end zone in the last minute, was instrumental in ripping the crow...

After a home loss to the 49ers that ended their playoff run, the Philadelphia Eagles may face a coaching change.

Sam Darnold was right.The Seahawks quarterback and former 49ers backup told Brock Purdy on Jan. 3 that they’d see each other in a couple of...

The 49ers trailed 19-17 after a 33-yard field goal by Philadelphia’s Jake Elliott Sunday in the fourth quarter at Lincoln Financial Field.O...

By all rights, the San Francisco 49ers’ season should have ended in October. That’s when superstar linebacker Fred Warner’s ankle snapped ea...

Another case of sweet, sweet Eagles revenge.

The undermanned 49ers went to Philadelphia to open the playoffs and left with a victory, beating the Eagles 23-19 on Sunday evening at Linco...

The injury-hit San Francisco 49ers sent the reigning Super Bowl champion Philadelphia Eagles crashing out of the NFL playoffs on Sunday in a...

No one could have possibly imagined this a season ago.

PHILADELPHIA (AP) — Brock Purdy threw a go-ahead 6-yard touchdown pass to Christian McCaffery late in the fourth quarter, San Francisco used...

The 49ers head to top-seeded Seattle next weekend for an NFC divisional playoff game. The NFC West rivals split the season series.

Postseason football is defined by grit and narrow margins.The San Francisco 49ers looked right at home in that environment, beating the Eag...

The San Francisco 49ers confirmed the worst for their star tight end, George Kittle, during the team's game against the Eagles.