The San Francisco 49ers have received some crushing news on the status of Brock Purdy and Jauan Jennings.

Purdy isn't starting for the Week 3 showdown with the Cardinals.

SANTA CLARA — In his ninth NFL season, 49ers coach Kyle Shanahan has had some of his toughest games in the NFC West against the Arizona Card...

SANTA CLARA — The 49ers made moves Saturday that didn’t provide a lot of clarity as to whether Brock Purdy will be suited up for their home...

The Arizona Cardinals elevated offensive lineman Jake Curhan and defensive lineman Anthony Goodlow from the practice squad Saturday ahead of...

San Francisco 49ers wide receiver Ricky Pearsall was attacked by a teenager last year near Union Square in San Francisco. The culprit was in...

Six days a week, it seems as if nothing can go right for the San Francisco 49ers.But on Sundays so far this season, the job has been done....

The San Francisco 49ers battle the Arizona Cardinals in their home opener at Levi’s Stadium on Sunday, Sept. 21 at 1:25 p.m. PDT.The Niners...

SANTA CLARA – All-white throwback jerseys are to serve as the 49ers’ heat shield if Sunday’s home opener with Arizona turns into another sco...

With the Arizona Cardinals taking on the San Francisco 49ers in Week 3 (Sunday at 4:25 p.m. ET), is Kyler Murray a good bet to hit paydir...

Will Marvin Harrison Jr. cash his Week 3 anytime TD player prop when the Arizona Cardinals clash with the San Francisco 49ers on Sunday a...

Purdy missed last Sunday’s 26-21 49ers win over the Saints in New Orleans. 

TEMPE — The San Francisco 49ers won’t be the only force going against the Arizona Cardinals this week.Adversity has taken centerstage and...

SANTA CLARA. Calif. (AP) — Quarterback Brock Purdy is “highly unlikely” to start on Sunday for the San Francisco 49ers as he deals with a to...

SANTA CLARA — Whether the quarterback is Mac Jones or Brock Purdy, it’s all about forward progress for the 49ers.Purdy was officially liste...