The San Francisco 49ers face division rivals the Los Angeles Rams on Sunday, Nov. 9 at 1:25 p.m. PT at Levi’s Stadium in Santa Clara.The 49...

When the San Francisco 49ers lost another key defensive player for the season when rookie Mykel Williams went down with a knee injury, star...

"I want them to have sad eyes."

SANTA CLARA – Six weeks after aggravating his toe injury, Brock Purdy is still not reclaiming his starting role for Sunday’s visit by the Lo...

"At some point, you're running out of weeks."

The 49ers need their franchise quarterback, writes SFGATE columnist Eric Ting.

SANTA CLARA — Brock Purdy is practicing for an eventual return as the 49ers’ quarterback. How eventual? No neon sign is indicating a comebac...

A former 49ers, Raiders, Chargers, and Buccaneers linebacker whose brothers and son played in the NFL has died.

SANTA CLARA – No savior is rushing onto the 49ers’ practice field this week in the wake of Tuesday’s NFL trade deadline.Unless it’s Bryce H...

A biotech company Tom Brady invested in reportedly got him a second dog.

The front office did not make a last-minute splash.

The NFL trade deadline is less than two hours away.

"I was doing whatever I could to get to San Francisco."

The San Francisco 49ers are heading into Tuesday’s trade deadline needing more than a minor transaction.They don’t need a single, solitary...

Sights and sounds that would have been unimaginable in the heyday of the Giants-49ers rivalry left Jon Runyan Jr. with a pit in his stomach.