San Francisco 49ers quarterback Brock Purdy and wide receiver Jauan Jennings have been downgraded from questionable to out and will not play...

The 49ers lose yet another starter on offense.

The Milwaukee Brewers could clinch their third straight National League Central title on Sunday afternoon when they play the decisive contes...

SANTA CLARA — In his ninth NFL season, 49ers coach Kyle Shanahan has had some of his toughest games in the NFC West against the Arizona Card...

In the Week 3 game between the San Francisco 49ers and the Arizona Cardinals at 4:25 p.m. ET on Sunday, will Brian Robinson Jr. hit paydi...

Brice Turang's decisive 10th-inning RBI single lifted the visiting Milwaukee Brewers past the St. Louis Cardinals 3-2 Saturday -- and pushed...

The Arizona Cardinals elevated offensive lineman Jake Curhan and defensive lineman Anthony Goodlow from the practice squad Saturday ahead of...

Six days a week, it seems as if nothing can go right for the San Francisco 49ers.But on Sundays so far this season, the job has been done....

St. Louis Cardinals third baseman Nolan Arenado was determined to overcome his persistent shoulder pain and resume playing before the season...

The San Francisco 49ers battle the Arizona Cardinals in their home opener at Levi’s Stadium on Sunday, Sept. 21 at 1:25 p.m. PDT.The Niners...

SANTA CLARA – All-white throwback jerseys are to serve as the 49ers’ heat shield if Sunday’s home opener with Arizona turns into another sco...

Nolan Arenado hit a three-run double to spur the St. Louis Cardinals to a 7-1 victory over the visiting Milwaukee Brewers on Friday.,Brendan...

TEMPE — The San Francisco 49ers won’t be the only force going against the Arizona Cardinals this week.Adversity has taken centerstage and...

SANTA CLARA. Calif. (AP) — Quarterback Brock Purdy is “highly unlikely” to start on Sunday for the San Francisco 49ers as he deals with a to...

Arizona Cardinals right guard Will Hernandez ended his 2024 season with a knee injury on Week 5. Recovery encroached on his free agency, an...