Los Angeles Rams wide receiver Puka Nacua hit an NFL milestone on "Thursday Night Football" against San Francisco 49ers.

INGLEWOOD, Calif. — The 49ers squandered leads throughout an epic night at SoFi Stadium, up until the final play of overtime Sunday.The Ram...

The San Francisco 49ers entered Thursday's game at the Los Angeles Rams without many key pieces, including franchise quarterback Brock Purdy...

INGLEWOOD, Calif. (AP) — Eddy Piñeiro hit a 41-yard field goal in overtime before the San Francisco defense stopped Kyren Williams on fourth...

The 49ers simply cannot escape the injury bug that has hit them hard for the second season in a row.

The 49ers might have deserved four more points.

It's been a rough broadcast for Al Michaels and Kirk Herbstreit.

Brock Purdy might be back later than expected.

Week 5 kicks off tonight on Thursday Night Football with a battle between the Rams and the 49ers in Inglewood.How to Watch Thursday Nigh...

Week 5 of the 2025 NFL season starts with a Thursday Night Football game between two NFC West teams, the San Francisco 49ers and the Los Ang...

Kristin Juszczyk, wife of San Francisco 49ers fullback Kyle Juszczyk, turned the Niners rival jersey into a creative outfit for San Francisc...

Mac Jones turned a lot of heads with his outfit selection for the Thursday Night Football game between the San Francisco 49ers and the LA Ra...

49ers fans were expected to make up the majority of the crowd for Thursday's game.

Thursday Night Football presents a classic NFC West showdown between two 3-1 squads as the 49ers vs Rams kicks off week 5. One of the most i...

The San Francisco 49ers travel to Los Angeles on Thursday night hoping an injury-riddled offense can hold up against the Rams' ninth-ranked...