Monday Night Football brings an interconference matchup that puts the San Francisco 49ers on the road against the Indianapolis Colts. This g...

Week 16 wraps up with a matchup between a playoff team and one trying to keep playoff hopes alive.

"That's the last guy they want to see," an NFL insider said.

Claire Kittle, who is married to 49ers tight end, George Kittle, said it "really hit home" when San Francisco briefly released veteran fullb...

The wildest storyline of the NFL season continues tonight as 44-year-old quarterback Philip Rivers will start at quarterback for the second...

New users can score a Kalshi promo code to make trades on prediction markets like Monday Night Football’s matchup between the 49ers and Colt...

It’s time for Monday Night Football!The Colts and 49ers close out Week 16 tonight with playoff implications at stake. Here’s a look at s...

“If they said, you had to do this or die? Yeah, you could pull off something.”

Did anyone actually watch Colts quarterback Philip Rivers play football last week?Checking in with the national media and the hellscape tha...

The San Francisco 49ers are taking on the Indianapolis Colts at 5:15 p.m. PDT on Dec. 22 at Lucas Oil Stadium on Monday Night Football.The...

Pittsburgh's win means the Chicago Bears and San Francisco 49ers clinched spots in the playoffs.

The San Francisco 49ers (10-4) bring a four-game winning streak into a matchup against the Indianapolis Colts (8-6) on Monday, December 22...

The 49ers clinched a playoff berth Sunday courtesy of the Pittsburgh Steelers.When the Steelers held on to beat the Detroit Lions 29-24 Sun...

The San Francisco wideout posted a video of himself going on a joyride in his Cadillac on Saturday, ripping through the South Bay and hittin...

Around the AFCNo problems, Houston. Six weeks ago, who could have foreseen the AFC South being one of the best races out there and not incl...