Mizzou opens as road favorite for Border War clash with Kansas ...Middle East

While a handful of games still remain on the slate for Week 1, many are already shifting their attention to Week 2 of the young college football season.

That is especially the case for those in the central U.S., because the Border War returns to Lawrence, Kansas, this Friday.

Missouri will visit its rivals looking to make it two straight wins over KU, and Eli Drinkwitz’ bunch has opened as a -6.5 favorite according to DraftKings.

With both teams having started their 2026 campaigns at 1-0 following comfortable victories over FCS opponents, the stakes are being raised to the highest level this week. Across all sports, a loss in the Border War is a depressing reality to accept, and neither side is eager to feel that this weekend.

After Beau Pribula (now of Virginia) and Jalon Daniels (now of Tampa Bay) started on either side of this matchup last fall, Ole Miss transfer Austin Simmons (Mizzou) and Isaiah Marshall (Kansas) will be the signal-callers for the 2026 edition of the rivalry. Simmons will be hoping to replicate MU’s 42-31 victory that occurred in Columbia last year.

The all-time series record between the Tigers and Jayhawks stands at 59-54-9 in favor of the former, but a trait of any good rivalry is debate over wins/losses, and that certainly exists in this one.

Prediction Markets How many regular season games will Mizzou win? Learn more about Prediction Markets Kalshi 6+ wins 73% 7+ wins 52% 8+ wins 30% 9+ wins 24% Predict

Mizzou opens as road favorite for Border War clash with Kansas Saturday Down South.

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